Papillary lesions of the breast can be one of the most challenging aspects of mammary pathology because of a wide morphologic spectrum that may be encountered in these lesions. An unusual breast tumor has been first classified as "breast tumor resembling the tall cell variant of papillary thyroid carcinoma" and subsequently renamed "tall cell variant of papillary breast carcinoma". To our knowl...

Background: Fine needle aspiration (FNA) has led to a decrease in unnecessary surgeries for thyroid nodules. This study was designed to compare diagnostic value of FNA and frozen section methods in the follicular lesions. Methods: This is a cross-sectional study based on the medical records of 42 patients who were referred to surgery clinic of Rasool-e-Akram hospital in Tehran with complain...

OBJECTIVE To report oncological cases (excluding those related to breast cancer) for which radioguided surgery has been used in combination with the Radioguided Occult Lesion Localization technique. INTRODUCTION Radioguided surgery enables a surgeon to identify lesions or tissues that have been preoperatively marked with radioactive substances. The Radioguided Occult Lesion Localization techn...

abstract introduction: cancer stem cells are a small subpopulation of cells within a tumor which are responsible for maintaining the tumor mass. a number of factors such as oct-4 that govern the fate of adult stem cells also play a role in malignant cell transformation. oct-4 is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis ...

Background: Ultrasound guided core needle biopsy is becoming a gold standard in the work up of suspicious breast lesion. In Iraq, radiologists are not taking lead performance. Objectives: To evaluate radiologist performance highlighting precession and accuracy procedure, concordance ultrasound histopathology, identifying challenges facing during procedure. Subjects Methods: A prospective study ...

background: fine needle aspiration (fna) has led to a decrease in unnecessary surgeries for thyroid nodules. this study was designed to compare diagnostic value of fna and frozen section methods in the follicular lesions. methods: this is a cross-sectional study based on the medical records of 42 patients who were referred to surgery clinic of rasool-e-akram hospital in tehran with complaint of...

BACKGROUND It has been shown that CD44 variants are differentially expressed in normal and neoplastic breast tissues. The diagnostic value of these markers in distinguishing benign from malignant breast lesions has not been well examined. AIMS To evaluate the diagnostic value of CD44s in distinguishing between intraductal papillomas and papillary carcinomas of the breast, which may be difficu...

Papillary carcinoma of the thyroid constitutes 80% of thyroid malignancies in adults. Females are affected at least twice as often as males. It metastasizes to distant sites very rarely, but to the cervical nodes quite often. Occasionally metastatic lymph node enlargement is the sole presenting feature. t.3.6.7 The tumor is slow growing and sometimes the patient has good survival even in s...

Breast carcinoma in men is extremely rare; it represents 0.6% of all breast carcinomas and less than 1% of all malignancies in men [1]. Intraductal papillary carcinoma (IPC) is also a rare form of breast cancer, accounting for 0.5–1% of all breast cancers [2]. IPC in man is an extremely rare disease with only very few case reports published in the literature so far [3-5]. IPC accounts for 5 to ...

The management of breast intraductal papillary neoplasms of the breast poses a challenge for clinicians. Intraductal papillary carcinoma and papilloma resemble in their clinical features. The aim of this study was to determine whether a combination of clinical factors could be used to accurately identify intraductal papillary carcinoma. 644 patients diagnosed by breast intraductal papillary neo...