Receptor-dependent uptake mechanisms for low-density lipoprotein (LDL) were studied in rabbit liver parenchymal and non-parenchymal cells. Hybridization studies with a cDNA probe revealed that mRNA for the apo (apolipoprotein) B,E receptor was present in endothelial and Kupffer cells as well as in parenchymal cells. By ligand-blotting experiments we showed that apo B,E-receptor protein was pres...

conclusions it seems that in advanced cases of cf, at older ages and with lack of appropriate medical care, severity, prevalence, and appearance of lung lesions do not follow a definite specific pattern. therefore, a similar study is suggested in older patients with a larger sample size for comparison of results. results all studied patients had bronchiectasis and peribronchial wall thickening ...

BACKGROUND Increased airway wall thickness (AWT) and parenchymal lung destruction both contribute to airflow limitation. Advances in computed tomography (CT) post-processing imaging allow to quantify these features. The aim of this Dutch population study is to assess the relationships between AWT, lung function, emphysema and respiratory symptoms. METHODS AWT and emphysema were assessed by lo...

Objectives: The aim of the study was to investigate relationship between body mass index and ultrasound-measured subcutaneous adipose tissue (SCAT) thickness, in order propose an alternative non-invasive inexpensive method measure fat. We also evaluated liver size existence hepatosteatosis, investigated whether there a measurements (BMI), SCAT measurements. Methods: Height, weight, arm SCAT, um...

The technique of transbronchial lung biopsy (TBLB) has expanded the diagnostic yield of bronchoscopy . In this article we are presenting 54 patients with diffuse pulmonary parenchymal involvement who underwent this procedure during six years between June 1980 and December 1989. The diagnostic yield of this technique in diffuse pulmonary parenchymal disease is great and was 66 percent exclu...

Precision-cut liver slices (PCLS) are an ex vivo model for metabolism and toxicity studies. However, data on the maintenance of the morphological integrity of the various cell types in the slices during prolonged incubation are lacking. Therefore, our aims were to characterize morphological and functional changes in rat PCLS during five days of incubation in a rich medium, RegeneMed®, and a sta...

INTRODUCTION Both ventricular and parenchymal devices are available for measurement of intracranial pressure (ICP). The Hummingbird(®) Synergy Ventricular System is a novel device allowing multi-parametric neurological monitoring, including both ventricular and parenchymal ICP. The purpose of this study is to compare the congruence of the device's ventricular and parenchymal ICP readings. MET...

1. Hepatic uptake of low-density lipoprotein (LDL) in parenchymal cells and non-parenchymal cells was studied in control-fed and cholesterol-fed rabbits after intravenous injection of radioiodinated native LDL (125I-TC-LDL) and methylated LDL (131I-TC-MetLDL). 2. LDL was taken up by rabbit liver parenchymal cells, as well as by endothelial and Kupffer cells. Parenchymal cells, however, were res...