At the Mayo Health System in LaCrosse, Wisconsin, there are >1000 infant total parenteral nutrition (TPN) orders placed per year. It is the most complicated order that the pharmacy fills, so a recent peer-review article in Pediatrics moved a group of us to action at our center to buy or develop a TPN calculator. We did this because no stand-alone commercial calculators were available to us, and...

Immunological studies were carried out on 7 neonates maintained on total parenteral nutrition for periods ranging from 14 to 31 days after surgery for correction of gastrointestinal anomalies. IgM and IgA levels were high in all patients but IgG levels were low, compared with normal values. Total leucocyte counts, absolute lymphocyte counts, and T- and B-lymphocytes in all patients were similar...

The benefits of early enteral feeding (EEN) have been demonstrated in gastrointestinal surgery. But, the impact of EEN has not been elucidated yet. We assessed the postoperative nutritional status of patients who had undergone pancreaticoduodenectomy (PD) according to the postoperative nutritional method and compared the clinical outcomes of two methods. A prospective randomized trial was under...

OBJECTIVE To know those predictive factors of hyperglycemia that could guide  us the design of a parenteral nutrition and it could avoid later complications associated with it. Methods: A prospective observational study was designed; adult hospitalized patients who received total parenteral nutrition at least 48 hours were included. Nutritional and pharmacotherapeutic follow-up were  performed ...

OBJECTIVE The aim of this study was to assess the clinical efficacy of alanine-glutamine dipeptide-supplemented total parenteral nutrition defined by the occurrence of nosocomial infections. Secondary parameters included Sequential Organ Failure Assessment score, hyperglycemia and insulin needs, intensive care unit and hospital length of stay, and 6-month mortality. DESIGN Multicenter, prospe...

OBJECTIVE To assess the difference between early enteral nutrition (EEN group) and total parenteral nutrition (TPN group) after total gastrectomy for gastric cancer. METHOD The nutrition index, liver function, patient generated subjective global assessment (PG-SGA) score, the post-operation complications, the hospital stay and hospitalization expense of the postoperative patient after total g...

Acute pancreatitis is a disease with varying severity. Patients with the mild form do not require nutritional support because oral intake is resumed rapidly. Studies on nutritional support in acute pancreatitis have included patients with both mild and severe disease. In this heterogeneous group, total parenteral nutrition did not improve outcome compared with no nutrition at all. This is cause...

A case of peritoneal mucinous carcinomatosis in a patient who suffered a Hirschsprung disease 30 year before is presented. TH present condition caused an irreversible intestinal obstruction and the patients received home parenteral nutrition without unremarkable complications longer than two years.

Consumption of food and drink is a fundamental part of North American culture. “All-you-can-eat” diners and lavish Thanksgiving turkey dinners are as American as Mom and apple pie. Eating and drinking is a valued social activity; we derive our strength from eating, and for many, the ability to eat and drink symbolizes life itself. The development of artificial nutrition has allowed us to feed p...

The nutrient formulas used for parenteral nutrition are highly complex admixtures of multiple solutions, infused by the IV route to patients who are unable to receive nutrition by mouth or by the enteral route. The administered products contain macronutrients (amino acids, dextrose, and lipids), electrolytes (sodium, potassium, calcium, phosphate, magnesium, chloride, and acetate), micronutrien...