In microfluidics mixing of different fluids is a highly non-trivial task due to the absence of turbulence. The dominant process allowing mixing at low Reynolds number is therefore diffusion, thus rendering mixing in plain channels very inefficient. Recently, passive chaotic micromixers such as the staggered herringbone mixer were developed, allowing efficient mixing of fluids by repeated stretc...

A bioluminescent-cell-based microfluidic device for sensing toxicants in drinking water was designed and fabricated. The system employed Vibrio fischeri cells as broad-spectrum sensors to monitor potential systemic cell toxicants in water, such as heavy metal ions and phenol. Specifically, the chip was designed for continuous detection. The chip design included two counter-flow micromixers, a T...

Sample mixing is difficult in microfluidic devices because of laminar flow. Micromixers are designed to ensure the optimal use of miniaturized devices. The present study aims to design a chaotic-advection-based passive micromixer with enhanced mixing efficiency. A serpentine-shaped microchannel with sinusoidal side walls was designed, and three cases, with amplitude to wavelength (A/λ) ratios o...

Efficient mixing at the microscale remains a formidable engineering challenge. Recent advancement and proliferation of Lab-on-a-Chip (LOC) and Micro Total Analysis Systems (μTAS) has demanded accelerated development and demonstration of novel micromixers as successful mixing is critical to device performance. Passive techniques such as chaotic advection and shear thinning as well as active meth...

This paper proposes a new "twisted" 3D microfluidic mixer fabricated by a laser writing/microfabrication technique. Effective and efficient mixing using the twisted micromixers can be obtained by combining two general chaotic mixing mechanisms: splitting/recombining and chaotic advection. The lamination of mixer units provides the splitting and recombination mechanism when the quadrant of circl...