Background Quality of life or more correctly health-related quality of life is currently receiving more attention in biomedical literature and outcome studies. However, there are several issues that we should be dealt with. First, measuring quality of life needs valid and reliable instruments. In addition, it is important to know how we conceptualize quality of life and reproductive health. Fin...

    Background: The aim of this study is to evaluate the geometry of the distal femur and the proximal tibia in the osteoarthritic knee using 3D reconstructive CT scan imaging. Methods: 449 patients with knee osteoarthritis were treated surgically in our center with patient-specific technology total knee arthroplasty. Preoperatively, all the patients underwent a CT scan according to a standard ...

clinical application of embryonic stem (es) cells faces difficulties regarding tissue rejection as well as ethical limitations. one solution for these issues is to reprogram somatic cells by the injection of their nucleus into an enucleated oocyte or zygote. however, technical complications and ethical considerations have impeded the therapeutic implications of this technology. an approach whic...

background:  this study presents patient specific and organ dose estimation in computed tomography (ct) imaging of thorax directly from patient ct image using monte carlo simulation.  patient's ct image is considered as the patient specific phantom and the best representative of patient physical index in order to calculate specific organ dose. materials and methods: egsnrc /beamnrc monte c...

To achieve local control of malignant pediatric bone tumors and to provide satisfactory oncological results, adequate resection margins are mandatory. The local recurrence rate is directly related to inappropriate excision margins. The present study describes a method for decreasing the resection margin width and ensuring that the margins are adequate. This method was developed in the tibia, wh...

BACKGROUND Sarcomas are associated with a relatively high local recurrence rate of around 30 % in the pelvis. Inadequate surgical margins are the most important reason. However, obtaining adequate margins is particularly difficult in this anatomically demanding region. Recently, three-dimensional (3-D) planning, printed models, and patient-specific instruments (PSI) with cutting blocks have bee...

OBJECTIVES To assess the accuracy of patient-specific instruments (PSIs) versus standard manual technique and the precision of computer-assisted planning and PSI-guided osteotomies in pelvic tumour resection. METHODS CT scans were obtained from five female cadaveric pelvises. Five osteotomies were designed using Mimics software: sacroiliac, biplanar supra-acetabular, two parallel iliopubic an...