A simplified technic for the determination of serum protein-bound iodine (PBI) is presented. Endogenouslylabeled 1131 PBI is completely recovered. The technic is basedon the method of Barker et al. (1) and includes the following modifications: The number of washesof the precipitated serum proteins are decreased. Unashed iodide standards are used in a sodium carbonate solution rather than an int...

A new organic-inorganic hybrid, [Pb(2)I(4)(C(4)H(13)N(3))](n), was obtained by the reaction of C(4)N(3)H(10) and PbI(2) at room temperature. The structure is a three-dimensional polymer resulting from the association of PbI(6) octa-hedra and a mixed lead organic-inorganic PbI(4)(C(4)N(3)H(13)) coordination polyhedron. Both Pb atoms, two I atoms and one N atom lie on a mirror plane. N-H⋯I hydrog...

Polybenzimidazole (PBI)-based high-temperature proton exchange membranes (PEMs) offer many advantages that aid in a simplified fuel cell system design. Such benefits include high resistance to fuel impurities (most notably carbon monoxide), fast electrode kinetics, and simplified water and thermal management due to operational temperatures above 120 ◦C.[1] As a result of its intrinsic physicoch...

Nucleophilic substitution of 1,6,7,12-tetrachloro perylene bisimide (PBI) with n-butanethiol provided a novel, highly twisted PBI bearing four sulphur coordination sites at the bay positions, from which silver and palladium complexes were prepared.

During recent years the determination of the protein-bound iodine (PBI) in the serum or plasma has been used with increasing frequency as a diagnostic aid. Various limits have been suggested for the serum PBI concentration in euthyroidism. The range most frequently recorded in the literature is from 4 to 8 gamma per cent of PBI. These values are not fiducial expressions of full statistical anal...

We present a comparison for high-resolution imaging with a laboratory source between grating-based (GBI) and propagation-based (PBI) x-ray phase-contrast imaging. The comparison is done through simulations and experiments using a liquid-metal-jet x-ray microfocus source. Radiation doses required for detection in projection images are simulated as a function of the diameter of a cylindrical samp...

Ixodes ricinus ticks and mice can be infected with both Borrelia burgdorferi sensu stricto and Borrelia garinii. The effect of coinfection with these two Borrelia species on the development of murine Lyme borreliosis is unknown. Therefore, we investigated whether coinfection with the nonarthritogenic B. garinii strain PBi and the arthritogenic B. burgdorferi sensu stricto strain B31 alters muri...

The self-assembly of perylene bisimide (PBI) dyes bearing oligo ethylene glycol (OEG) units in water affords responsive functional nanostructures characterized by their lower critical solution temperature (LCST). Tuning of the LCST is realized by a supramolecular approach that relies on two structurally closely related PBI-OEG molecules. The two PBIs socially co-assemble in water and the result...

The incorporation of iodide into proteins (PBI) and lipids (LBI) of horse thyroid slices was measured in various conditions. Their dependency on the concentration of extracellular iodide was strikingly different. For PBI the relationship was biphasic with a decrease above 10 microM, likely to correspond to the Wolff-Chaikoff effect. On the contrary, LBI increased as a function of iodide concent...

We previously reported neuroprotective activity of the botanical anti-cancer drug candidate PBI-05204, a supercritical CO2 extract of Nerium oleander, in brain slice and in vivo models of ischemic stroke. We showed that one component of this neuroprotective activity is mediated through its principal cardiac glycoside constituent, oleandrin, via induction of the potent neurotrophic factor brain-...