PURPOSE To measure the level of oxytocin in serum and prostate cancer (PCa) tissue and study its effect on the proliferation of PCa cells. RESULTS Oxytocin level in serum was significantly increased in PCa patients compared with the no-carcinoma individuals. Additionally, the levels of oxytocin and its receptor were also elevated in the PCa tissue. However, no significant difference existed a...

Factor analysis (FA) is a statistical technique similar to principal component analysis (PCA) for explaining the variance in a data set in terms of underlying linear factors. Unlike PCA, however, FA has not been widely exploited for face or object recognition. This paper explains the differences between PCA and FA, and confirms that PCA outperforms FA in a standard face recognition task. Howeve...

Primary cutaneous amyloidosis (PCA) is a localized skin disorder that is characterized by the abnormal deposition of amyloid in the extracellular matrix (ECM) of the dermis. The pathogenesis of PCA is poorly understood. The objective of the present study was to survey proteome changes in PCA lesions in order to gain insight into the molecular basis and pathogenesis of PCA. Total protein from PC...

Objective. To compare the performance of multiparametric resonance imaging/ultrasound fusion targeted biopsy (MRI/US-TBx) to a combined biopsy strategy (MRI/US-TBx plus 24-core transperineal template saturation mapping biopsy (TTMB)). Methods. Between May 2012 and October 2015, all patients undergoing MRI/US-TBx at our institution were included for analysis. Patients underwent MRI/US-TBx of sus...

BACKGROUND We investigated associations between statin use begun before prostate cancer (PCa) diagnosis and PCa recurrence/progression and PCa-specific mortality (PCSM) in a prospective, population-based cohort study. METHODS The analysis included 1,001 PCa patients diagnosed in 2002-2005 in King County, Washington. Statin use was assessed at the time of diagnosis using a detailed in-person i...

this paper presents a deterministic approach for performance assessment of different province’s road safety level at iran. a data envelopment analysis (dea) model considering undesirable input and output indices and a multivariate statistical method, principle component analysis (pca) are used in this paper, while previous studies do not use composite pca-dea method and undesirable input and ou...

PURPOSE Abnormal DNA methylation is associated with many human cancers. The aim of the present study was to identify novel methylation markers in prostate cancer (PCa) by microarray analysis and to test whether these markers could discriminate normal and PCa cells. EXPERIMENTAL DESIGN Microarray-based DNA methylation and gene expression profiling was carried out using a panel of PCa cell line...