there exists compelling evidence that toll-like receptor 3 (tlr3) agonists can directly affect human cancer cells. the aim of this study was to investigate anti-cancer effects of tlr3 agonist in human breast cell line. we assessed potential effects of poly (a:u) on human breast cell line (mda-mb-231)  on a dose-response and time-course  basis. human breast cell line  mda-mb-231  was treated wit...

background human papillomavirus (hpv) is associated with various benign and malignant lesions including genital condyloma and anogenital cancer. the presence of hpv-dna was studied in archival biopsies of high- and intermediate-risk lesions for cervical carcinoma in women referred to mirza hospital in tehran. patients and methods totally, 105 iranian archived biopsies collected during february ...

(See the articles by Ogawa et al., on pages 782–8, and by Schleiss et al., on pages 789–98.) It has been 50 years since Smith [1] and Weller et al. [2] separately reported the isolation and propagation of a cytopath-ogenic virus from tissues of infants with cytomegalic inclusion disease. In the intervening half century, much has been learned about congenital cytomegalovirus (CMV) infection, as ...

LETTERS Hepatitis B and C viral infections among STD clinic patients in India While many studies from other countries 1 2 document hepatitis B virus (HBV) and hepatitis C virus (HCV) infection rates in STD clinic patients, very few data are available from India. In the present report, we have analysed the rate of HBV and HCV infections in STD patients by using serologi-cal and molecular methods...

To study host gene activation by retroviral promotor insertion, a polymerase chain reaction (PCR) assay was developed. This method allows a sensitive and selective detection of chimeric provirus-host gene transcripts, hallmarks of insertional activation events, which does not rely on an induction of tumor cell growth. We analysed HIV-1 infected cells of a CD4+ T-cell line (H9), infected periphe...

abstract: ornithobacterium rhinotracheale (ort) has been identified as one of the emerging respiratory bacterial pathogens in turkey and chicken flocks. diagnosis of ort infection has been faced some difficulties in isolation and identification of the bacterium based on the biochemical properties. a reliable identification method that can be used in routine laboratory investigations is of impor...