نتایج جستجو برای: pediatric nephrotic syndrome
تعداد نتایج: 728920 فیلتر نتایج به سال:
Background: Nephrotic syndrome (NS) is the most common glomerular disease seen in pediatric age group. Objective: To study demographic, socioeconomic, related characteristics and physical examination including height, weight blood pressure correlation with frequency of relapses children steroid sensitive NS (SSNS). Methods: This a cross sectional that was conducted at Nephrology Consultation Cl...
Minimal Change Disease (MCD) is the leading cause of childhood Nephrotic Syndrome (NS). Therefore in pediatrics nephrotic syndrome, most children beyond the first year of life will be treated with corticosteroids without an initial biopsy. Children with NS often display a number of calcium homeostasis disturbances causing abnormal bone histology, including hypocalcemia, reduced serum vitamin D...
Nephrotic syndrome (NS) is a common glomerular pathology encountered in pediatric practice. The main clinical signs are massive proteinuria, hypoalbuminemia, hyperlipidemia, and edema. Among all cases of NS, 75 % children have histological variant lesions the form minimal change disease that sensitive to hormone therapy, but easily leads relapse steroid dependence. These often need extend time...
Tyrosine kinase inhibitors (TKI) were developed as the targeted therapy of cancer and are considered an important treatment of Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) or Ph+ acute lymphoblastic leuke-mia (ALL). 1,2 As the use of TKIs has increased, its side effects have also been reported. A few cases of children who developed nephrotic syndrome following treatment...
the hematological malignancies associated with nephrotic syndrome are mainly hodgkin’s and non-hodgkin’s lymphomas and chronic lymphocytic leukemia. acute myelogenous leukemia (aml) has rarely been described in associated with nephritic syndrome. we report a rare case of acute myelogenous leukemia who presented with nephrotic syndrome. a previously healthy 62-year-old man was admitted in nephro...
BACKGROUND AND OBJECTIVES Up to 95% of children presenting with steroid-resistant nephrotic syndrome in early life will have a pathogenic single-gene mutation in 1 of 24 genes currently associated with this disease. Others may be affected by polymorphic variants. There is currently no accepted diagnostic algorithm for clinical genetic testing. The hypothesis was that the increasing reliability ...
1 Stony Brook Children’s Hospital, Stony Brook, NY, United States, 2 Department of Nephrology, Children’s Hospital of Pittsburgh, Pittsburgh, PA, United States, 3 Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States, 4 Division of Pediatric Nephrology, Children’s Hospital at Montefiore, Albert Einstein College of Medicine, New York, NY, United S...
A chronic, progressive disorder Steroid Resistant Nephrotic Syndrome (SRNS) accounts for 10-20% of all children with Nephrotic Syndrome. It is a heterogeneous disorder comprised of persistent edema, proteinuria, hypoalbuminemia and hyperlipidemia. Treatment for steroid-resistant nephrotic syndrome (SRNS) is challenging and children who suffer from SRNS require aggressive treatment to achieve re...
Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the first line of treatment. A significant number of patients with SRNS progress to end-stage renal disease if remission is not achieved. For these chi...
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