Retroperitoneum is a relatively uncommon site for pediatric teratomas. Rarely, such tumors can have an intraspinal extension and few cases of retroperitoneal teratomas associated with spinal dysraphism have been reported. Teratomas consist of tissues arising from all three embryonic layers. However, mature renal tissues in the form of glomeruli and tubules are sparingly found in teratomas. A 15...

Spinal intradural malignant peripheral nerve sheath tumors (MPNSTs) in children are extremely rare, with only five reported cases in the literature. A 9-year-old female with neurofibromatosis type 2 (NF-2) presented with right hip pain and severe weakness of bilateral legs for 3 months. Magnetic resonance (MR) imaging revealed multiple intradural masses at the T11-L2, L4, and L5-S5 level respec...

Compared with brain tumors in adults, a much higher percentage of pediatric brain tumors arise in the posterior fossa, which includes the brain stem and cerebellum. While astrocytoma’s can be found elsewhere in the brain, the majority are found in the posterior fossa. These infratentorial astrocytoma tumors comprise as many as two thirds of all pediatric brain tumors [1]. An astrocytoma is typi...

Objective: To observe the therapeutic effect of microsurgery through hemilaminectomy approach on extramedullary spinal tumor. Methods: Hemilaminectomy was performed on 45 patients with extramedullary spinal tumor. Of the 45 patients, 35 had intradural extramedullary spinal tumors and 10 dumbbell-shaped spinal tumors. Spinal schwannoma occurred in 36 patients and spinal meningioma in 9 patients....

Multiple primary tumors in a single patient are relatively rare when four or more distinct lesions are considered. Herein, we report a case of woman with four different primary tumors: meningioma, renal angiomyolipoma, spinal ependymoma and high-grade soft tissue sarcoma. There was no family history and hereditary syndrome. The genetic analysis was completely normal. To best of our knowledge, t...

As an uncommon subtype of meningioma, chordoid meningioma (CM) of the spinal canal is extremely rare. There have been only two reported cases of intraspinal CM in the literature, and this lesion has not been previously reported in the pediatric age group. To the best of our knowledge, the present study reports the first case of spinal chordoid meningioma in a pediatric patient. A 12-year-old fe...

Abstract Diffuse midline gliomas H3K27-altered are pediatric tumors associated with dismal survival after diagnosis that characterized by their ability to infiltrate the entire central nervous system. We show extent of tumor invasion and metastatic progression represent critical adverse prognostic factors affecting DMG patients. Yet, no genetic alterations associate patterns. therefore used gli...