The preparations and characterization of polypyrrole – polyethylene glycol (PPy-PEG) films are reported in this paper. The composite films were synthesized by electrochemical method in 0.2 mol·L-1 Py and 5% PEG in 0.2 mol·L-1 oxalic acid. The electrochemical behaviour of PPy and PPy-PEG coatings has been investigated in phosphate buffer solution (PBS) by cyclic voltammetry, Tafel plots and elec...

Polyethylene glycol (PEG) grafting has a great potential to create nonfouling and nonthrombogenic surfaces, but present techniques lack versatility and stability. The present work aimed to develop a versatile PEG grafting method applicable to most biomaterial surfaces, by taking advantage of novel primary amine-rich plasma-polymerized coatings. Star-shaped PEG covalent binding was studied using...

Percutaneous endoscopic gastrostomy (PEG) is a relatively safe and effective method of providing nutrition to patients with neurologic deficits or proximal gastrointestinal pathology. Complications that follow this common procedure include dislodgement, dysfunction, infection and aspiration. The "Buried Bumper Syndrome" (BBS) is an infrequent and late complication of PEG tubes that can result i...

We present a simple and widely applicable method to fabricate micro- and nanochannels comprised entirely of crosslinked polyethylene glycol (PEG) by using UV-assisted irreversible sealing to bond partially crosslinked PEG surfaces. The method developed here can be used to form channels as small as approximately 50 nm in diameter without using a sophisticated experimental setup. The manufactured...

The preclinical development of peptidyl drugs for cancer treatment is hampered by their poor pharmacologic properties and cell penetrative capabilities in vivo. In this study, we report a nanoparticle-based formulation that overcomes these limitations, illustrating their utility in studies of the anticancer peptide NuBCP-9, which converts BCL-2 from a cell protector to a cell killer. NuBCP-9 wa...

Word spotting is to make searchable unindexed image documents by locating word/words in a doc-ument image, given a query word. This problem is challenging, mainly due to the large numberof word classes with very small inter-class and substantial intra-class distances. In this paper, asegmentation-based word spotting method is presented for multi-writer Persian handwritten doc-...

Many homogeneous assays are complicated by the adsorption of probe molecules by the surface of reaction vessels, which are often made of polypropylene or polystyrene-based plastics. To solve this problem, many protein and surfactant-based blocking agents are used. However, these blockers may interfere with intended assays by sequestering transition-metal ions, inducing protein denaturing, gener...

Direct percutaneous endoscopic jejunostomy (DPEJ) is a useful method for the delivery of nutrition in patients with a variety of gastrointestinal (GI) problems [1–3]. However, DPEJ using standard colonoscopes or the push technique remains a technically challenging procedure, with success rates of about 68% in expert hands [2]. Herein, we present the key steps to conducting a successful DPEJ usi...

Preparation of poly (ethylene glycol) (PEG)-grafted chitosan is essential for improving the biocompatibility and water solubility of chitosan. Presently available methods for this have limitations. This article describes a new method for preparing PEGylated chitosan nanoparticles. For this chitosan was chemoselectively modified using a novel scheme at the C6 position of its repeating units by P...