Bone morphogenic protein 2 (BMP-2)/HeparinlAlkali phosphatase actiyitylReal-time PCR. Therapeutic radiation causes bone damage and may increase fracture risks in treatment fbr head-andneck cancer and in pelvic irradiation. [[1iese properties can also be used fbr prevention of heterotopic ossification in hip arthroplasty, To evaluate the effects of ionizing radiation on osteoblast differentiatio...

INTRODUCTION Worldwide, bacterial resistance to antibiotic therapy is a major concern for the medical community. Antibiotic resistance mainly affects Gram-negative bacteria that are an important cause of lower urinary tract infections (LUTIs). Pelvic irradiation for prostate cancer is a risk factor for LUTIs. Cranberry extract is reported to reduce the incidence of LUTIs. The prophylactic role ...

AIM Our aim is to compare the toxicity, pelvic nodal relapse, and overall survival of whole bladder irradiation only to the standard technique of whole pelvis irradiation followed by bladder boost in patients with muscle-invasive bladder carcinoma undergoing bladder preservation protocol. MATERIAL AND METHOD A total of 60 patients with transitional cell carcinoma, stage T2-3, N0, M0 bladder c...

AIMS AND BACKGROUND Neutron rays produce high linear energy transfer radiation, which has particular radiobiological characteristics. The aim of the study was to observe the curative effects and complications of external irradiation combined with californium-252 (252Cf) neutron intraluminal brachytherapy for treatment of cervical carcinoma. METHODS AND STUDY DESIGN From December 2000 to Decem...

In a complete geographic series of 155 cases of primary uterine sarcomas, prophylactic pelvic irradiation was used as standard postoperative therapy in the majority of the cases. Vaginal brachytherapy was also added as a boost. The histology was leiomyosarcoma in 62 cases (40%), carcinosarcoma in 60 (39%), endometrial stromal sarcoma in 25 (16%), and other types in 8 cases (5%). The primary sur...

BACKGROUND Chinese medicine Wuzi Yanzong pill (WZYZP) was firstly documented in ancient Chinese medical works "She Sheng Zhong Miao Fang" by Shi-Che Zhang in 1550 AD. The traditional herbal formula is widely used in treating nephrasthenia lumbago, prospermia, erectile dysfunction and male sterility. The present study was to explore the effects of WZYZP on ionizing irradiation-induced testicular...

Cervical cancer is a highly preventable malignant disease and if detected early has a good prognosis and can be cured by surgery or radiotherapy alone. In western countries about 40,000 women die from advanced cervical cancer per year, in developing countries, however, where early diagnosis is the exception, the death rate from advanced cervical cancer is about six times as much. The treatment ...

BACKGROUND Local tumor spread of cervical cancer is currently considered as radial progressive intra- and extracervical permeation. For radical tumor resection or radiation the inclusion of a wide envelope of tumor-free tissue is demanded. However, this concept may lead to considerable treatment-related morbidity and does not prevent local relapse. We propose an alternative model of local tumor...

Abdominoperineal resection is a standard method of low-rectum carcinoma treatment. It is associated with significant morbidity and mortality rates, which decreased with the development of preoperative diagnostic procedures, new surgical techniques and new surgical instruments. In this article, laparoscopic pelvic peritonization was used after laparoscopic rectum amputation for low-rectum carcin...