The mould genus, Penicillium, is known to be a significant source of environmental aero-allergens. One important allergen from Penicillium citrinum, Pen c 2, has been identified by means of two-dimensional immunoblotting using IgE-containing patients' sera. This novel allergen was cloned, sequenced and expressed in Escherichia coli. The cloned cDNA encodes a large 457-amino acid protein precurs...

achieved simply by stopping therapy until symptoms subsideusually in four to five days-and then resuming therapy gradually with increasing doses over several weeks. We have used n-pen. successfully now in two patients with welldocumented histories of penicillin allergy. Previously it was our belief that D-pen. would be effective only in preventing de novo stone formation or progression of stone...

This cross-sectional study aimed to investigate if the Tono-Pen, Schiøtz and Perkins tonometers could be used interchangeably in general practice for measuring elevated intraocular pressure. A total of 74 eyes of 37 paediatric patients under general anaesthesia were checked with all 3 tonometers. All of the tonometers gave significantly different measurements from each other. However, with a me...

The availability of a large sample database is very important to design high accuracy classifiers for handwritten character recognition. Collecting image samples from human writers and practical documents is expensive particularly for large character sets, like with East-Asia-languages. We can therefore take advantage of existing on-line databases to generate additional off-line images. This pa...

The use of handwriting provides a natural way of interacting with small portable computers. However, in order to capture handwritten text on-line special input devices are necessary. Therefore, Munich & Perona [13] proposed to use visual input for pen-based computers. Writing can then be performed on ordinary paper and pen trajectories are automatically extracted from image sequences recorded d...

A comfortable way of digitizing a new music composition is by using a pen-based recognition system, in which the digital score is created with the sole effort of the composition itself. In this kind of systems, the input consist of a set of pen strokes. However, it is hitherto unclear the different types of strokes that must be considered for this task. This paper presents an experimental study...