We describe and contrast several different bootstrapping procedures for penalized spline smoothers. The bootstrapping procedures considered are variations on existing methods, developed under two different probabilistic frameworks. Under the first framework, penalized spline regression is considered an estimation technique to find an unknown smooth function. The smooth function is represented i...

A general framework for smooth regression of a functional response on one or multiple functional predictors is proposed. Using the mixed model representation of penalized regression expands the scope of function-on-function regression to many realistic scenarios. In particular, the approach can accommodate a densely or sparsely sampled functional response as well as multiple functional predicto...

Ordered categorial predictors are a common case in regression modeling. In contrast to the case of ordinal response variables, ordinal predictors have been largely neglected in the literature. In this article penalized regression techniques are proposed. Based on dummy coding two types of penalization are explicitly developed; the first imposes a difference penalty, the second is a ridge type r...

In this paper the asymptotic behavior of penalized spline estimators is studied using bivariate splines over triangulations and an energy functional as the penalty. The rate of L2 convergence is derived, which achieves the optimal nonparametric convergence rate established by Stone (1982). The asymptotic normality of the penalized spline estimators is established, which is shown to hold uniform...

In multilocus association analysis, since some markers may not be associated with a trait, it seems attractive to use penalized regression with the capability of automatic variable selection. On the other hand, in spite of a rapidly growing body of literature on penalized regression, most focus on variable selection and outcome prediction, for which penalized methods are generally more effectiv...