BACKGROUND The morbidity and mortality of surgical aortic valve replacement are increased in elderly patients with multiple high-risk comorbid conditions. Therefore, a prospective, single-center, nonrandomized study was performed in high-risk patients with aortic valve disease to evaluate the feasibility and safety of percutaneous implantation of a novel self-expanding aortic valve bioprosthesi...

Background—The morbidity and mortality of surgical aortic valve replacement are increased in elderly patients with multiple high-risk comorbid conditions. Therefore, a prospective, single-center, nonrandomized study was performed in high-risk patients with aortic valve disease to evaluate the feasibility and safety of percutaneous implantation of a novel self-expanding aortic valve bioprosthesi...

Background In contrast to surgical aortic valve replacement pre procedural assessment of aortic, aortic annulus diameter and prosthesis size is essential for successful percutaneous interventional valve therapy. Among different imaging modalities multislice-computed tomography (MSCT) and transesophageal echocardiography (TEE) are routinely used for patient screening. We sought to evaluate the d...

Background—The morbidity and mortality of surgical aortic valve replacement are increased in elderly patients with multiple high-risk comorbid conditions. Therefore, a prospective, single-center, nonrandomized study was performed in high-risk patients with aortic valve disease to evaluate the feasibility and safety of percutaneous implantation of a novel self-expanding aortic valve bioprosthesi...

introduction: aortic valve sclerosisis considered as a manifestation of coronary atherosclerosis. recent studies demonstrated an association between aortic valve sclerosis and obstructive coronary artery disease. the purpose of this study was to evaluatethe correlation betweenaortic valve sclerosis andobstructive coronary artery disease and the extent of coronary artery disease in patients hosp...

OBJECTIVES This study sought to assess the effectiveness of a novel percutaneous method to treat left ventricular assist device (LVAD)-associated severe aortic insufficiency (AI) in a series of patients determined to be poor reoperative candidates. BACKGROUND The increased use of continuous-flow LVAD in advanced heart failure has led to marked changes in the management of patients with this c...

A previously published two-part study described an engineering design of a percutaneous aortic valve (PAV) replacement system, which utilizes a novel temporary aortic valve (TAV) support to improve procedural outcomes and safety. Conceptually, this investigational approach can promote accurate PAV placement, procedural hemodynamic stability, smaller catheter delivery system, reduction in PAV re...

The incidence of valvular aortic stenosis has increased over the past decades due to improved life expectancy. Surgical aortic valve replacement is currently the only treatment option for severe symptomatic aortic stenosis that has been shown to improve survival. However, up to one third of patients who require lifesaving surgical aortic valve replacement are denied surgery due to high comorbid...

Developmental efforts to achieve percutaneous catheterbased therapies for cardiac valve repair and replacement have advanced rapidly over the past several years. A variety of methods to treat mitral regurgitation (MR) and to replace aortic and pulmonic valves have already been successfully employed in patients. These innovative clinical transcatheter valve therapies were anticipated more than a...

in recent socio-economic state it is not possible to have different sets of prosthetic cardiac valves available in the operating room before open-heart surgery for valvular replacement. in this study the diameter of the aortic valve ring measured in 2-d echocardiography was compared with the size of the aortic prosthetic valves implanted for the patients with aortic valvular disease. the purpos...