We propose an architecture based on a hybrid E2E-ERN approach allowing ERN protocols to be inter-operable with current IP-based networks. Without introducing complex operations, the resulting E2E-ERN protocol provides inter and intra protocol fairness and benefits from all ERN advantages when possible. We detail the principle of this novel architecture, called IP-ERN, and show that this archite...

At the Olympic level, differences in performance are typically less than 0.5%. This helps explain why many contemporary elite endurance athletes in summer and winter sport incorporate some form of altitude/hypoxic training within their year-round training plan, believing that it will provide the "competitive edge" to succeed at the Olympic level. The purpose of this paper is to describe the pra...

The practice of enhancing athletic performance through the use of ergogenic aids or by extraneous artificial means is as old as competitive sport itself. Although the abuse of such substances has been historically problematic, very little research assessing the attitudes of strength/power athletes concerning ergogenic aids exists. As national anti-doping organizations (NADOs) adopt preventative...

Lipid-drug conjugates (LDCs) are drug molecules that have been covalently modified with lipids. The conjugation of lipids to drug molecules increases lipophilicity and also changes other properties of drugs. The conjugates demonstrate several advantages including improved oral bioavailability, improved targeting to the lymphatic system, enhanced tumor targeting, and reduced toxicity. Based on t...

Actovegin is a deproteinized serum extract of bovine origin, and in recent years it has been used widely in treating sport injuries with many anecdotal reports of success. However, the use of Actovegin in sport medicine has caused a substantial amount of controversy, especially concerning its supposed oxygen-enhancing capacity and an anecdotal belief that its use can increase an athlete's perfo...