نتایج جستجو برای: peripheral mononuclear cell pbmc

تعداد نتایج: 1813954  

The purpose of the current study was to evaluate the anti-inflammatory activity of tetramethlpyrazine on oxazolone-induced colitis mice. Spleen mononuclear cells (SMC), lamina propria mononuclear cells (LPMC) and peripheral blood mononuclear cells (PBMC) were isolated from oxazolone-induced colitis and normal mice. The colitis cells treated by oxazolone were randomly divided into model, low dos...

Journal: :Journal of virology 2000
I S Choi R Hokanson E W Collisson

Feline immunodeficiency virus (FIV) causes AIDS-like symptoms in infected cats. Concanavalin A (ConA)-stimulated peripheral blood mononuclear cells (PBMC) from chronically FIV strain PPR-infected cats readily expressed FIV. In contrast, when PBMC from these animals were stimulated with irradiated, autologous antigen-presenting cells (APC), at least a 10-fold drop in viral production was observe...

Journal: :iranian journal of allergy, asthma and immunology 0
gholam reza shariati department of medical genetic, national institute for genetic engineering and biotechnology (nigeb), ghasem ahangari department of medical genetic, national institute for genetic engineering and biotechnology (nigeb), arash hossein-nezhad endocrinology and metabolism research center, tehran university of medical sciences, tehran, iran seyed mohammad asadi department of psychiatric, rozbeh hospital, tehran university medical sciences, tehran, iran farzaneh pooyafard department of psychiatric, rozbeh hospital, tehran university medical sciences, tehran, iran hamid reza ahmadkhaniha tehran psychiatric institute, iran university of medical sciences, tehran, iran

serotonin receptors are involved in pathophysiology of schizophrenia and may mediate other neurotransmitter effects. we investigated serotonin receptors gene expression in peripheral blood mononuclear cells (pbmc) of naïve schizophrenic patients, before and after treatment. also serotonin receptor gene expression was compared in two treatment groups including haloperidol and olanzapine. the pbm...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Michael E Burczynski Natalie C Twine Gary Dukart Bonnie Marshall Manuel Hidalgo Walter M Stadler Theodore Logan Janice Dutcher Gary Hudes William L Trepicchio Andrew Strahs Fred Immermann Donna K Slonim Andrew J Dorner

PURPOSE Given their accessibility, surrogate tissues, such as peripheral blood mononuclear cells (PBMC), may provide potential predictive biomarkers in clinical pharmacogenomic studies. In leukemias and lymphomas, the prognostic value of peripheral blast expression profiles is clear; however, it is unclear whether circulating mononuclear cells of patients with solid tumors might yield profiles ...

1998
Tae-Won Lee Jai-Kyung Park Jae-Hyung Ahn Chun-Gyoo Ihm Myung-Jae Kim

OBJECTIVES To investigate the possible role of mononuclear cells and their products in the pathogenesis of IgA nephropathy, in vitro expression of ICAM-1 on cultured mouse mesangial cell (MC) was examined after stimulation with mononuclear cell culture supernatant from patients with IgA nephropathy. METHODS Peripheral blood mononuclear cells (PBMC) were isolated and cultured from 18 patients ...

Abbas Basiri, Amir Hossein Danesh Manesh, Flora Forouzesh, Hodjattallah Rabbani, Mahmood Jeddi-Tehrani, Mahyar Ostadkarampour,

Background: The ectopic expression of receptor tyrosine kinase Ror1 has been reported in patients with hematological malignancies such as chronic lymphocytic leukemia and acute lymphoblastic leukemia. Here we report, for the first time, expression of ROR1 gene in both tumor tissues and peripheral blood mononuclear cells (PBMC) from patients with renal cancer (RC). Methods: In the current study,...

Journal: :Journal of virology 2002
Tomasz Laskus Marek Radkowski Agnieszka Bednarska Jeffrey Wilkinson Debra Adair Marek Nowicki Georgia B Nikolopoulou Hugo Vargas Jorge Rakela

Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.

Journal: :Infection and immunity 2001
L Guilherme S E Oshiro K C Faé E Cunha-Neto G Renesto A C Goldberg A C Tanaka P M Pomerantzeff M H Kiss C Silva F Guzman M E Patarroyo S Southwood A Sette J Kalil

T-cell molecular mimicry between streptococcal and heart proteins has been proposed as the triggering factor leading to autoimmunity in rheumatic heart disease (RHD). We searched for immunodominant T-cell M5 epitopes among RHD patients with defined clinical outcomes and compared the T-cell reactivities of peripheral blood and intralesional T cells from patients with severe RHD. The role of HLA ...

2017
Sri Agus Sudjarwo Koerniasari Eraiko Giftania Wardani Sudjarwo Koerniasari

Objective It has long been known that chickens, like mammals, are capable of producing antigen-specific immunoglobulin Y (IgY), which functions similar to IgG. The present study was performed to investigate the activity of IgY anti-Mycobacterium tuberculosis on proliferation, interleukin (IL)-2, and interferon (IFN)-γ expression of rat peripheral blood mononuclear cells (PBMCs). Materials and...

Journal: :Infection and immunity 2002
Maria Angeles Gomez Morales Raffaella Mele Massimo Sanchez Daria Sacchini Marzia De Giacomo Edoardo Pozio

Cell-mediated immunity during the muscular phase of Trichinella infection in humans was studied. Cell proliferation, the phenotypic changes in the T-cell population, and expression and production of cytokines were examined by using peripheral blood mononuclear cells (PBMC) collected at different times postinfection from 10 individuals who had acquired Trichinella spiralis and five individuals w...

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