This PET study concerns changes in regional cerebral blood flow (rCBF) associated with orientation discrimination tasks and with simple detection of the stimulus. The difference in rCBF between discrimination and detection represents the discrimination, or 'task', component of the response. We have examined how such differences are influenced by the position of the visual stimulus and also how ...

QSAR of the binding affinities of [2-phenylimidazo[1,2-a]pyridin-3-yl]acetamide derivatives (Fig. 1) with central and peripheral (from cortex and ovary) benzodiazepine receptors has been explored using physico-chemical parameters. Attempt has been made to explore the structural and/or physico-chemical requirements of the compounds that are responsible for the selective action against peripheral...

Chromosome ends in Saccharomyces cerevisiae are positioned in clusters at the nuclear rim. We report that Ctf18, Ctf8, and Dcc1, the subunits of a Replication Factor C (RFC)-like complex, are essential for the perinuclear positioning of telomeres. In both yeast and mammalian cells, peripheral nuclear positioning of chromatin during G1 phase correlates with late DNA replication. We find that the...

background: finding the safe location of spinal cord for cerebrospinal fluid (csf) during surgical procedures is very important due to its various nature for each patient as well as its potential peripheral nervous system hazards. the aim of this study was to find the relationship between the location of conus medullaris (cm) and gender, age and body mass index (bmi) in order to minimize the po...

Abstract Background Using phantoms and clinical studies in prone hanging breast imaging, we assessed the image quality of a commercially available dedicated PET (dbPET) at detector’s edge, where mammary glands near chest wall are located. These compared to supine PET/CT images same subjects. Methods A phantom with four spheres (16-, 10-, 7.5-, 5-mm diameter) was filled 18 F-fluorodeoxyglucose s...

Our group has developed a biodegradable drug delivery device (micro-implant) for long-term slow intraocular release of methotrexate (MTX) that can be implanted in the peripheral vitreous. The purpose of this study was to assess the position of the implanted devices and the status of the adjacent vitreous and peripheral retina over time using B-scan ocular ultrasonography (US). In each of the ei...

OBJECTIVE The positioning of a patient in bed may directly affect their respiratory mechanics. The objective of this study was to evaluate the respiratory mechanics of mechanically ventilated patients positioned with different head angles hospitalized in an intensive care unit. METHODS This was a prospective physiological study in which static and dynamic compliance, resistive airway pressure...

When observers are asked to localize the peripheral position of a small probe with respect to the mid-position of a spatially extended comparison stimulus, they tend to judge the probe as being more peripheral than the mid-position of the comparison stimulus. This relative mislocalization seems to emerge from differences in absolute localization, that is the comparison stimulus is localized mor...

Peripheral galvanic vestibular stimulation (GVS) has been shown to temporarily ameliorate left spatial neglect [1]. Specifically, anodal (facilitatory) stimulation over the left mastoid bone coupled with cathodal (inhibitory) over the right mastoid reduces visuospatial‐neglect scores in line cancellation [2] and line bisection tasks [3, 4]. This montage increases activity in the left vestibular...