Horseradish peroxidase and chlorite, NaC102, are able to catalyze chlorination of monochlorodimedone to form dichlorodimedone. Catalytic amounts of horseradish peroxidase act to disproportionate chlorite forming chlorine dioxide and chloride ion. The chlorine dioxide thus formed is responsible for the chlorination of monochlorodimedone. It was previously thought (Chiang, R., Rand-Meir, T., Maki...

A versatile ligninolytic peroxidase has been cloned from Pleurotus eryngii and its allelic variant MnPL2 expressed in Aspergillus nidulans, with properties similar to those of the mature enzyme from P. eryngii. These include the ability to oxidize Mn(2+) and aromatic substrates, confirming that this is a new peroxidase type sharing catalytic properties of lignin peroxidase and manganese peroxid...

Peroxidase catalyzes oxidatic reactions (in which oxygen is the electron acceptor) as well as the classic peroxidatic reactions (in which hydrogen peroxide is the electron acceptor) (4, 10). There is considerable evidence that the enzyme which catalyzes the oxidatic degradation of the plant growth hormone, indole-3acetic acid, is a peroxidase (8). Recently Yang (12, 13) and Ku et al. (5) have d...

Administration of a single dose of estradiol to immature rats gives rise to the appearance of substantial amounts of peroxidase (donor:hydrogen-peroxide oxidoreductase, EC 1.11.1.7) enzyme activity in the uterus. This enzyme induction, which is inhibited by administration of actinomycin D and cycloheximide, can be detected at 4 hr after administration of estradiol, reaches a maximum level by 20...

Ganoderma applanatum belongs to the group of white-rot fungi, due to a well-developed ligninolytic enzyme system. White-rot fungi have attracted great scientific attention in recent years, especially with respect to their enzymatic potential for the bioremediation of persistent pollutants. Contrary to G. lucidum, which medicinal properties, as well as ligninolytic enzyme system have been extens...

Enzyme mimetics have attracted wide interest due to their inherent enzyme-like activity and unique physicochemical properties, as well promising applications in disease diagnosis, treatment monitoring. Inspired by the attributes of nonheme iron enzymes, synthetic models were designed mimic capability investigate catalytic mechanisms. Herein, metal-organic gels (Fe-MOGs) with horseradish peroxid...

We obtained spectroscopic evidence in support of salicylate-dependent inactivation of horseradish peroxidase-C. Addition of salicylate to the enzyme arrested at a temporal inactive state (Compound III) in the presence of H2O2, resulted in rapid and irreversible inactivation of the enzyme yielding verdohemoproteins (P-670). Multiple roles for salicylate in peroxidase-catalyzed reactions are disc...

Toshio Kaneko, MD, Third Department of Internal Medicine, Yamaguchi University School of Medicine, Koguchi, Ube Yamaguchi 755 (Japan) Oxidative damage of red cell membrane is known to be accelerated in sickle cell disease. However, the exact mechanism of this acceleration is unclear. We have read with interest the recent article entitled ‘Selenium and Glutathione Peroxidase Levels in Sickle Cel...