Neuroblastomas are the most common extracranial solid tumors in children and have a unique feature of neuronal differentiation. Peroxisome proliferator-activated receptor (PPAR)-γ is reported to neuroprotective effects addition having antitumor various cancers. Thus, we aimed clarify role PPAR-γ agonist antagonist malignant neuroblastomas, which also possess features. In MYCN-amplified neurobla...

Introduction: Obesity is a metabolic disease with an increase both in cell size (hypertrophy) and number (hyperplasia) following differentiation of new adipocytes. Adipogenesis well-orchestrated program which mitotic clonal expansion (MCE) occurs the early step followed by late terminal one. Methods: Aim study was to evaluate vitro effects cyanidin-3-O-glucoside (C3G), anthocyanin present many ...

The present study was conducted to investigate the anti-oxidant and anti-obesity activities of Centella asiatica hot-water extract (CHE). Total polyphenol content radical scavenging activity were evaluated for CHE, 14.4 mg GAE/g DM 82.6% measured, respectively. Lipase inhibition, an marker, measured as 68.1%, confirming that triglyceride hydrolysis significantly inhibited by CHE. To mechanism, ...