Alix is a cytosolic protein in mammalian cells that was originally identified on the basis of its association with pro-apoptotic signaling. More recent evidence has established that Alix has a hand in regulating other cellular mechanisms, including endocytic membrane trafficking and cell adhesion. Although Alix appears to participate directly in these various activities, the role it plays in ea...

The work presented here aims at understanding the nature, epigenesis and function of personality types (here called behavioral profiles) in birds, focusing on a wild bird species, the great tit (Parus major). Lines bidirectionally selected for exploration show a wide array of social and non-social behavioral differences, and also some differences in physiological parameters. Line differences in...

Sir William Osler (Figure 1) arrived in Britain in 1905 determined not only to guide Oxford medicine as its Regius Professor but also to improve the standard of postgraduate medicine throughout Britain. He felt that each county hospital should have a postgraduate department, using the argument that without postgraduate education a doctor was stale in five years, in the rut by ten years, and by ...

BACKGROUND Certain personalities are ascribed to physicians. This research aims to measure the extent to which physicians identify with three predetermined personalities (workaholic, Type A and control freak) and to explore links to perceptions of professional performance, and wellness outcomes. METHODS This is a cross-sectional study using a mail-out questionnaire sent to all practicing phys...

Believability is a basic requirement for non-player characters of videogames. Players enjoy characters with personalities that reflect human behavior, specially if those personalities combine well with players’ temperaments. This paper explains a model for customizing automatically non-player characters (NPC) according to the players temperament, which is obtained before the game session. The m...

Robert Carson's principle of complementarity asserts that the behavioral styles of interaction partners tend to complement each other by encouraging individuals to act opposite in terms of dominance and similar in terms of warmth. The principles of complementarity further hypothesize that as relationships progress through multiple interactions, the behavioral styles of its members will be alter...

Drawing inspiration from social science and psychology, a computational model of a personality model for a Believable, Adaptable, Socially Intelligent Character (BASIC) has been designed, implemented and tested to drive chimpanzees in a multi-agents scenario. The BASIC model can be customized to create different personalities that are able to trigger empathic responses in human spectators, othe...

Recent research indicates that people respond socially to computers and perceive them as having personalities. Software agents are artifacts that particularly embody those qualities most likely to elicit social responses : fulŽlling a social role, using language, and exhibiting contingent behavior. People’s disposition to respond socially can be so strong that they may perceive software agents ...