abstract background: dyes are visible materials and are considered as one of the hazardous components that make up the industrial waste. dye compounds in natural water, even in very low concentrations, will lead to environmental problems. azo dyes are compounds with one or more –n=n– groups and are used in textile industry. because of its low price, solubility, and stability, azo dyes are widel...

Rudimentary understanding of biological significances of various genomic alterations is causing slow paced translation of cancer genome sciences to personalized medicine. Comprehensive databases of genetic variations associated to effective cancer prevention approaches, early detection and treatment responses are required to successfully utilize the large amounts of information generated by cur...

Radiomics is an emerging field in quantitative imaging that uses advanced imaging features to objectively and quantitatively describe tumour phenotypes. Radiomic features have recently drawn considerable interest due to its potential predictive power for treatment outcomes and cancer genetics, which may have important applications in personalized medicine. In this technical review, we describe ...

Despite advances in molecular characterization and lung cancer treatment in recent years, treatment options for patients diagnosed with squamous cell carcinoma of the lung (SCC) remain limited as actionable mutations are rarely detected in this subtype. This article reviews potential molecular targets and associated novel agents for the treatment of advanced SCC in the era of personalized medic...

The management of locally advanced rectal cancer has grown in both complexity and quality since the first proctectomy. What once was a malignancy with fairly consistent treatment algorithm for decades, recent paradigm shift care these patients led to more personalized, multidisciplinary approach variations timing, sequence, duration, potential exclusion multimodality therapies. This review summ...

Lung cancer remains the leading cause of cancer-related deaths both in Russia and worldwide, it is often diagnosed at a late stage median survival with traditional first-line chemotherapy platinum-based regimens does not exceed one year. The discovery activating mutations epidermal growth factor receptor ( EGFR ) gene offered first opportunity for personalized treatment advanced non-small cell ...

Using a computer to answer questions has been a human dream since the beginning of the digital era. A first step towards the achievement of such an ambitious goal is to deal with natural language to enable the computer to understand what its user asks. The discipline that studies the connection between natural language and the representation of its meaning via computational models is computatio...