نتایج جستجو برای: pharmaceutical active ingredient
تعداد نتایج: 521346 فیلتر نتایج به سال:
C.G. Wilson and P.J. Crowley (eds.), Controlled Release in Oral Drug Delivery, Advances in Delivery Science and Technology, DOI 10.1007/978-1-4614-1004-1_2, © Controlled Release Society 2011 Abstract Oral drug delivery remains the mainstay of patient treatment although the candidate drugs of the new millennium are becoming increasingly difficult to formulate for good systemic absorption. The ar...
This paper presents the results obtained after studying the thermal stability and decomposition kinetics of perindopril erbumine as a pure active pharmaceutical ingredient as well as a solid pharmaceutical formulation containing the same active pharmaceutical ingredient (API). Since no data were found in the literature regarding the spectroscopic description, thermal behavior, or decomposition ...
Exploring the Role of Anti-solvent Effects during Washing on Active Pharmaceutical Ingredient Purity
Washing is a key step in pharmaceutical isolation to remove the unwanted crystallization solvent (mother liquor) from active ingredient (API) filter cake. This study looks at strategies for optimal wash selection, which minimizes dissolution of API product crystals while preventing precipitation or impurities. Selection solvents avoid both these phenomena can be challenging but essential mainta...
CONTEXT Prussian blue, ferric hexacyanoferrate is approved for (oral) treatment of internal contamination with radioisotopes of cesium or thallium. Cyanide makes up 35-40% of Prussian blue's molecular composition; thus, cyanide may be released during transit through the digestive tract under physiological pH conditions. OBJECTIVES The purpose of this study is to assess the long-term stability...
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