BACKGROUND Although Group A beta hemolytic streptococcus (GABHS) can cause bacterial pharyngitis, the most common etiology is viral; despite this viral etiology, antibiotics are commonly prescribed for this infection in industrialized countries. We investigated the prevalence of GABHS in adult pharyngitis patients from lower socioeconomic settings in Karachi, Pakistan, how often antibiotics are...

BACKGROUND & OBJECTIVES There are no recent data from industrialised countries documenting the incidence and costs of group A streptococcal (GAS) pharyngitis. Such data are important in developing policy regarding management (e.g., whether or not to use antibiotics to treat sore throat) and in planning preventive strategies, including preparing for the arrival of GAS vaccines. The present study...

By use of molecular techniques, the genetic heterogeneity of 63 community pediatric pharyngeal group A streptococcal (GAS) isolates circulating within a 3-week period were compared with 17 contemporaneous invasive pediatric isolates. Pharyngitis isolates represented 16 pulsed-field gel electrophoresis (PFGE) patterns with 12 emm serotypes, and invasive isolates represented 10 PFGE patterns with...

Submit Manuscript | http://medcraveonline.com [1]. Streptococcal pharyngitis is most significant disease, and its peak incidence occurs in children, these infections impose the economic burden on the society [2]. The symptoms of streptococcal pharyngitis include a sore throat, pain in swallowing, fever, swollen, and tender lymph nodes in the neck and fatigue [3]. S. pharyngitis oftenly results ...

Group A streptococcus (GAS), or Streptococcus pyogenes, is the most common pathogen responsible for bacterial pharyngitis, which has the following characteristic clinical manifestations: fever, tender cervical lymphadenopathy, exudative pharyngeal discharge, and absence of common cold symptoms (cough, coryza, rhinorrhea, diarrhea, oral ulcer) [1, 2]. In addition to these Centor criteria, GAS ph...

We observed late-onset rashes in patients with group A beta-hemolytic streptococcal (GAS) pharyngitis. Of 1028 patients with GAS pharyngitis, which was principally treated with amoxicillin, we evaluated those who developed a late-onset rash and excluded those with scarlet fever alone. Twenty-one patients developed a rash (2.0%, 95% confidence interval, 1.3-3.1%), 7 to 20 days (median, 8 days) a...

www.aafp.org/afp Volume 88, Number 5 ◆ September 1, 2013 The Infectious Diseases Society of America (IDSA) has updated its 2002 guideline on managing group A streptococcal pharyngitis. The illness primarily occurs in children five to 15 years of age. Patients typically present with sudden onset of a sore throat, pain with swallowing, and fever. Examination shows tonsillopharyngeal erythema, oft...

OBJECTIVE To identify the best clinical decision rules (CDRs) for diagnosing group A streptococcal (GAS) pharyngitis in children. A combination of symptoms could help clinicians exclude GAS infection in children with pharyngitis. DESIGN Systematic review and meta-analysis of original articles involving CDRs in children. The Pubmed, OVID, Institute for Scientific and Technical Information and ...

BACKGROUND & OBJECTIVE Group A streptococcus (GAS) causes a wide array of human diseases. Epidemiological picture of streptococcal infection in India is not complete. Hence, disease burden due to GAS in 5-15 yr old school children in northern India was studied and emm typing of GAS isolates was carried out to help in designing prevention strategies. METHODS A cross-sectional survey was carrie...