Phenotypic switching is characterized as a virulence factor of Candida spp. This study was carried out to evaluate the phenotypic switching ability of C. krusei ATCC 14243 and to determine its effect on the biological properties, adherence capacity and susceptibility towards chlorhexidine digluconate (CHX). To induce switched generations C. krusei was cultured under nitrogen-depleted growth con...

INTRODUCTION The aim of this study was to identify a rapid and simple phenotypic method for extended-spectrum β-lactamase (ESBL) detection in Enterobacter cloacae. METHODS A total of 79 consecutive, non-repeated samples of E. cloacae were evaluated. Four phenotypic methods were applied for ESBL detection, results were compared to multiplex polymerase chain reaction (PCR) as the gold standard ...

background: pseudomonas aeruginosa is the causing agent of many hospital infections and metallo-beta-lactamases (mbl) are being reported with increasing frequency. the aim of this study was to determine the frequency of metallo-&beta-lactamases; (mbl) and vim-1 gene in multidrug-resistant strains of p. aeruginosa isolates and to compare the methods of phenotypic and molecular detection. materia...

contamination sites of pseudomonas fluorescenswere traced in the production line for milk pasteurization in a large dairy plant in shiraz, iran. samples of raw and pasteurized milk were collected at six sites along the line. all milk samples were incubated at 7°c until the aerobic plate count had reached 10 6 -10 7 cfu ml-1. colonies were picked randomly and identified. no growth of gram negati...

conclusions regarding the importance of metallo-beta-lactamase (mbl) produced by pseudomonas spp. isolated from hospitals, quick identification of clinical samples should be considered as an important and basic step to treat and control infections caused by pseudomonas spp. results strains with mic > 4 µg/ml were investigated by phenotypic and genotypic methods. in the current study the rate of...

background and objectives : the main cause of serious nosocomial infections is a gram-negative pathogen known as pseudomonas aeruginosa (p. aeruginosa). carbapenems are widely used as an appropriate treatment for these infections, however resistance to these agents has been observed and is increasing. metallo beta-lactamase (mbls) enzyme is one of the main causes of resistance to carbapenem. in...

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing correlations obtained from the disease history of more than 30 million patients in a Phenotypic Disease Network (PDN). We present evidence that the structure of the PD...