Two synthetic strategies for incorporating diiron analogues of [FeFe]-hydrogenases into short peptides via phosphine functional groups are described. First, utilizing the amine side chain of lysine as an anchor, phosphine carboxylic acids can be coupled via amide formation to resin-bound peptides. Second, artificial, phosphine-containing amino acids can be directly incorporated into peptides vi...

The effects of different types and concentrations of electron donors (glucose, starch, methanol and sodium acetate) on the formation of phosphine from anaerobic activated sludge that has been domesticated for a prolonged period were studied in small batch experiments. The results show that types and concentrations of electron donor have significant effects on the production of phosphine from an...

The objectives of this work were to assess phosphine resistance in insect populations (Tribolium castaneum, Rhyzopertha dominica, Sitophilus zeamais and Oryzaephilus surinamensis) from different regions of Brazil and to verify if the prevailing mechanism of phosphine resistance in these populations involves reduced respiration rates. Sixteen populations of T. castaneum, 15 of R. dominica, 27 of...

Abstract Cell-free protein synthesis (CFPS) enables the development of antibody conjugates, such as fluorophore conjugates and antibody-drug (ADCs), in a rapid straightforward manner. In first part, we describe cell-free antibodies containing fluorescent non-canonical amino acids (ncaa) by using pre-charged tRNA. second ncaa an orthogonal system, followed site-specific conjugation dye DyLight 6...

Bis(borane) adducts Acenap(PiPr2·BH3)(PRH·BH3) (Acenap = acenaphthene-5,6-diyl; 4a, R = Ph; 4b, R = ferrocenyl, Fc; 4c, R = H) were synthesised by the reaction of excess H3B·SMe2 with either phosphino-phosphonium salts [Acenap(PiPr2)(PR)](+)Cl(-) (1a, R = Ph; 1b, R = Fc), or bis(phosphine) Acenap(PiPr2)(PH2) (3). Bis(borane) adducts 4a-c were found to undergo dihydrogen elimination at room temp...

The red flour beetle is a cosmopolitan pest of stored grain and stored grain products. The pest has developed resistance to phosphine, the primary chemical used for its control. The reproductive output of survivors from a phosphine treatment is an important element of resistance development but experimental data are lacking. We exposed mated resistant female beetles to 0.135 mg/L of phosphine f...

The manufacture and application of aluminium phosphide fumigants pose risks of inhalation exposure to phosphine gas. This article presents a case report of suspected inhalation exposure to phosphine gas in a manufacturing facility for aluminium phosphide fumigants, which was associated with acute dyspnoea, hypotension, bradycardia and other signs of intoxication. These symptoms resolved within ...

background: aluminum phosphide (alp) poisoning is one of the most life threatening emergencies. in this study, demographic characteristics, clinical profiles and outcomes of a series of patients presented with alp poisoning in north iran are described. methods: the study was a retrospective descriptive medical chart review of alp poisoned patients who were admitted to internal ward of imam khom...

Mitochondria as an important organ in eukaryotic cells produced energy through oxidative phosphorylation and also played an important role in regulating the apoptotic signal transduction process. Importantly, mitochondria like nuclei also contained the functional DNA and were very sensitive to anticancer drugs which could effectively inhibit the synthesis of nucleic acid, especially the product...

A series of vanadium(III) complexes bearing monodentate tertiary phosphine ligands of the type VCl3(PRnPh3-n)2 (n = 0 (1a); n = 1 and R = Me (1b), Et (1c), iPr (1d), Cy (1e); n = 2 and R = Me (1f), Et (1g), Cy (1h)), and VCl3(PR3)2 (R = Cyp (2a), Cy (2b), nPr (2c), tBu (2d)) were synthesized and characterized. In the case of 1c, 1g and 2a single crystals were also obtained and their molecular s...