INTRODUCTION Oral mucositis is considered a severe complication in cancer patients receiving radiotherapy or chemotherapy for head and neck cancer. The aim of this review study was to assess the effect of low level laser therapy for prevention and management of oral mucositis in cancer patients. METHODS The electronic databases searched included Pubmed, ISI Web of Knowledge and Google scholar...

In a recent article by Sommer et al. in Annals of Translational Medicine, the authors make several key comments on our recent article in Scientific Reports entitled “Molecular pathway of near infrared laser phototoxicity involves ATF4 orchestrated ER stress” (1). Firstly, we would like to thank the authors for their laudatory, constructive comments, specifically appreciating the rigorous effort...

Photobiomodulation (PBM), often also known as low-level laser therapy, is a non-invasive method of treatment. It employs specific wavelength red and infrared light induces several physiological responses in cells tissues that form the foundation PBM. This treatment photochemically stimulates to produce chemicals, such adenosine triphosphate, reactive oxygen species, calcium ions, etc. contribut...

Photobiomodulation by light in the red to near infrared range (630-1000 nm) using low energy lasers or lightemitting diode (LED) arrays has been shown to accelerate wound healing, improve recovery from ischemic injury and attenuate degeneration in the injured optic nerve. At the cellular level, photoirradiation at low fluences can generate significant biological effects including cellular proli...

Light-emitting diode photobiomodulation is the newest category of nonthermal light therapies to find its way to the dermatologic armamentarium. In this article, we briefly review the literature on the development of this technology, its evolution within esthetic and medical dermatology, and provide practical and technical considerations for use in various conditions. This article also focuses o...