This study investigated radiation dose variations in pre-clinical irradiation due to the photon beam energy and presence of tissue heterogeneity. Based on the same mouse computed tomography image dataset, three phantoms namely, heterogeneous, homogeneous and bone homogeneous were used. These phantoms were generated by overriding the relative electron density of no voxel (heterogeneous), all vox...

1. INTRODUCTION X-ray sources on next generation low emittance/high brilliance synchrotrons such as the 7-GeV Advanced Photon Source (APS) (1) have unique properties which directly affect the design of the front end of the beam line. The most striking of these are the large peak photon power densities expected for the insertion device (ID) x-ray sources. Undulators. for example. can have highly...

Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

The third-generation synchrotron radiation (SR) facilities are storage ring-based facilities with many insertion devices and photon beamlines, and have low injection beam power, but extremely high stored beam power. The fourth-generation X-ray free electron laser (FEL) facilities are based on an electron Linac with a long undulator and have high injection beam power. Due to its electron and pho...

We coherently probe a quantum dot that is strongly coupled to a photonic crystal nano-cavity by scattering of a resonant laser beam. The coupled system’s response is highly nonlinear as the quantum dot saturates with nearly one photon per cavity lifetime. This system enables large amplitude and phase shifts of a signal beam via a control beam, both at single photon levels. We demonstrate photon...

Introduction: Treatment with megavoltage electron beams is ideal for irradiating superficial tumors because of their limited range in tissues. However, for electron treatment of extended areas, such as the chest wall, two or more adjacent fields can be used. Abutment of these fields may lead to significant dose in homogeneities in the junction region. The aim of this study is to offer a new met...

background: the electron contamination may reduce or even diminish the skin sparing property of the megavoltage beam. the detailed characteristics of contaminant electrons are presented for different field sizes and cases. materials and methods: the monte carlo code, mcnpx, has been used to simulate 18 mv photon beam from a varian linac-2300 accelerator. all dose measurements were carried out u...

PURPOSE Thermoluminescent dosimeters are used routinely for dosimetric measurements of photon and electron fields. However, no work has been published characterizing TLDs for use in combined photon and electron fields. This work investigates the response of TLD-100 (LiF:Mg,Ti) in mixed fields of photon and electron beam qualities. METHODS TLDs were irradiated in a 6 MV photon beam, 6 MeV elec...

Purpose: In the last years, some studies investigated dosimetric benefits of a free flattening filter for the photon mode in the radiotherapy field. This study aims to provide a theoretical study published and analysis of basic dosimetric properties for a Saturne 43 Linac head to implement free flattening filter beams clinically. Material and Methods: Thi...

background: monte carlo (mc) modeling of a linear accelerator is a prerequisite for monte carlo dose calculations in external beam radiotherapy. in this study, a simple and efficient model was developed for elekta sl-25 linear accelerator using mcnp4c monte carlo code materials and methods: the head of elekta sl-25 linac was simulated for 6 and 18 mv photon beams using mcnp4c mc code. energy sp...