Liver transplantation is the definite surgical treatment for patients with end-stage liver disease and acute liver failure that improves liver functions and survival. In recent years health-related quality of life has been accepted to be in relation with surgical success and has become to be used as an important assessment parameter not only after transplantation but also during the disease pro...

Chronic hepatitis B is a global health problem that leads to development of various complications, such as cirrhosis, liver cancer, and liver failure requiring liver transplantation. The recurrence of hepatitis B virus (HBV) post-liver transplantation is a major cause of allograft dysfunction, cirrhosis of the allograft, and graft failure. Patients with high viral load at the time of transplant...

context the pnpla3 i148m variant has been recognized as a genetic determinant of liver fat content and a genetic risk factor of liver damage progression associated with steatohepatitis. the i148m variant is associated with many chronic liver diseases. however, its potential association with inflammatory and autoimmune liver diseases has not been established. evidence acquisition we systemically...

epithelioid hemangioendothelioma (ehe) is a rare neoplasm of vascular origin which arises preferentially in soft tissue and bone, and rarely in the liver. its vascular nature is confirmed by positive staining for factor viii-related antigen and other endothelial cell markers (cd31, cd34) in addition to the pathologic characteristics of well-developed basal lamina, pinocytotic vesicles, and, mor...

Background The complex process of liver graft assessment is one point for improvement in transplantation. main objective this study to develop a tool that supports the surgeon who responsible donation decision-making whether accept or not using initial variables available it. Material and method Liver samples candidate transplantation after donor brain death were studied. All them evaluated “ s...

OBJECTIVES Liver transplantation has not increased with the number of patients requiring this treatment, increasing deaths among those on the waiting list. Models predicting post-transplantation survival, including the Model for Liver Transplantation Survival and the Donor Risk Index, have been created. Our aim was to compare the performance of the Model for End-Stage Liver Disease, the Model f...

tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. to date, there is no information on the pharmacokinetics of tacrolimus in iranian liver transplant recipients. this study was designed to determine pharmacokinetic properties of orally administe...