background: studies have shown that physalis alkekengi reduces implantation and induces antifertility in rat. in iranian traditional medicine it is believed that this plant has abortifacient and antifertility activities. objective: the goal of this study was to evaluate the effect of physalis alkekengi ripe fruit hydroalcoholic extract (pfe) on uterine contractility and its possible mechanism(s...

Physalis minima is an herbaceous plant and inhabitant of the porous and organic matter containing soil of bunds in crop fields, wastelands, around the houses, and on the roadsides. S. rolfsii is soil borne and it can infect over 500 plant species of different families. It is of interest to study the pathogenesis of S. rolfsii on P. minima. The S. rolfsii isolated from P. minima (physr1) was cha...

Clinical tests of the efficacy of various treatments of bluebottle (Physalia physalis) stings were conducted on 20 volunteers. Vinegar and aluminium sulphate solution (Stingose) gave a significant reduction in pain 15 minutes after application when compared with the control sites which were treated with sea water. The application of methylated spirits caused a significant increase in pain compa...

A new withanolide glycoside, 17beta-hydroxy-14, 20-epoxy-1-oxo-[22R]-3beta-[O-beta-D-glucopyranosyl]-witha-5, 24-dienolide (1), has been isolated from the whole plant of Physalis peruviana. Its identity was determined using a combination of spectroscopic data including 2D NMR techniques and chemical transformations.

Four withanolides (1-4) and two sucrose esters (5, 6) were isolated from the aerial parts of Physalis neomexicana. The structures of 1-6 were elucidated through a variety of spectroscopic techniques. Cytotoxicity studies of the isolates revealed that 2 inhibited human breast cancer cell lines (MDA-MB-231 and MCF-7) with IC50 values of 1.7 and 6.3 μM, respectively.

background: physalis alkekengi (p. alkekengi)has been used as an abortive plant in iranian traditional medicine for many years. objective: to investigate the effects of p.alkekengi on the fertility rate in female rats. material and methods: in this experimental study, 40 female albino rats were divided randomly into two groups; group 1/for investigating the implantation sites and group 2/ for i...

A novel withanolide, aromaphysalin A (1), possessing an exceptional C(11)-C(15) bond and an unprecedented 4,9-cyclized aromatic ring (ring A), is isolated from stems and leaves of Physalis angulata L. Its structure was determined by a combination of HRESIMS, 2D NMR spectra, and theoretical calculations. Compound 1 exhibited inhibitory activity on NO production with an IC50 value of 51.64 μM. A ...