Previous workers have emphasized the possibility that pregnancy-induced hypertension (PIH) is associated with a change of sexual partner. It is noted here that any such association is far weaker than that between PIH and fecundability (the probability of conceiving in a month at risk). This latter association is so strong as to suggest its closeness to a true cause. Of the determinants of fecun...

We assessed whether a pregnant woman who was born small for gestational age has increased risk of pregnancy-induced hypertension (PIH), and whether the same applies to a pregnant partner of a man who was born small for gestational age. We linked generational data from the medical birth registry of Norway (1967-2005). Female and male newborns were identified as parents with 197,716 and 131,959 f...

OBJECTIVE This study was conducted was to detect vascular endothelial growth factor (VEGF) levels in peripheral blood of patients with pregnancy-induced hypertension (PIH) syndrome and to investigate VEGF correlation with PIH occurrence. METHODS Double-antibody enzyme-linked immunosorbent assay and fluorescent quantitative polymerase chain reaction were used to detect VEGF levels in the perip...

To investigate the activation of particulate guanylate cyclase in pregnant women with pregnancy-induced hypertension (PIH), plasma levels of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and guanosine 3',5'-cyclic phosphate (cGMP) were measured by radioimmunoassays specific to each substance. Ten normal nonpregnant women, and 30 normal pregnant women, 17 pregnant women with...

Objective. In this study, we have assessed sympathovagal imbalance (SVI) by spectral analysis of heart rate variability (HRV) that contributes to the genesis of early-onset PIH. Methods. Body mass index (BMI), basal heart rate (BHR), blood pressure (BP) and HRV indices such as LFnu, HFnu, LF-HF ratio, mean RR, SDNN and RMSSD were assessed in normal pregnant women (Control group) and pregnant wo...

Introduction: Pregnancy induced hypertension is one of the most common causes of both maternal and fetal morbidity and mortality. This study aims to determine the feto-maternal outcome and correlation with severity of PIH. Material and methods: 250 cases of PIH were studied and divided according to severity. The maternal and fetal outcome parameters were documented and analysed using statistica...

The mean heart weight as a measure of arterial hypertension of patients who died from spontaneous intracerebral hemorrhage (primary intracerebral hemorrhage or PIH) was compared with that of controls from the same autopsy population. All patients with valvular or congenital heart disease or disease processes associated with myocardial infiltration were excluded. In 206 cases of PIH, hypertensio...

OBJECTIVES To test the hypothesis that pregnant women with high serum βhCG level and serum dyslipidemia in second trimester are more prone to develop subsequent Pregnancy Induced Hypertension (PIH). MATERIALS & METHODS One hundred pregnant women with singleton pregnancy between 14 and 20 weeks of gestation attending antenatal outpatient department (OPD) of SMCH were studied. Serum βhCG was es...

Background and Objectives:Chronic hypertension induces changes in the cardiac structure and function; however, the effects of transient hypertension are unclear. Pregnancy-induced hypertension (PIH) offers a natural and spontaneous model of this condition. Subjects and Methods:20 women, aged 30.3±5.1 years, with pregnancy-induced hypertension, defined as a blood pressure higher than 140/90 mmHg...