Our laboratory has demonstrated that Yorkshire placentae increase in size and surface area during the final third of gestation. In contrast, Meishan placental size remains constant during late gestation, but the density of blood vessels at the placental-endometrial interface increases markedly. Preliminary observations from our laboratory suggest that if one of two adjacent Meishan fetuses dies...

The relationships between genotype and placental traits, parity and litter weight (LW), and factors affecting these characteristics were investigated in this study. In total, 112 ewes (Romanov crossbred and local breeds) were utilized. One-way ANOVA was used for statistical comparison, and a Pearson correlation was used to determine the relationships between the variables. Significant differenc...

Gestational trophoblastic disease (GTD) represents a spectrum of lesions characterised by an abnormal proliferation of trophoblast, including complete hydatidiform mole, partial hydatidiform mole, invasive hydatidiform mole, choriocarcinoma, placental site trophoblastic tumour, epithelioid trophoblastic tumour, placental site nodule and plaque, and exaggerated placental site reaction. Complete ...

The insulin/insulin-like growth factor (IGF) system regulates fetal and placental growth and development. In maternal diabetes, components of this system including insulin, IGF1, IGF2 and various IGF-binding proteins are deregulated in the maternal or fetal circulation, or in the placenta. The placenta expresses considerable amounts of insulin and IGF1 receptors at distinct locations on both pl...

The mammalian placenta is the site of nutrient and gas exchange between the mother and fetus, and is comprised of two principal cell types, trophoblasts and endothelial cells. Proper placental development requires invasion and differentiation of trophoblast cells, together with coordinated fetal vasculogenesis and maternal vascular remodeling. Disruption in these processes can result in placent...

BACKGROUND We wanted to find the most frequent site of placental implantation at 18 weeks' gestation and placental migration during gestation. METHODS Placental location was identified in 2,526 singleton pregnancies at 18 weeks' gestation and characterized into nine groups. Placental migration in 1,336 of these pregnancies was assessed by serial ultrasonography. RESULTS At 18 weeks' gestati...