Although growth plate response to mechanical stress has been increasingly studied, our understanding of mechanical modulation of neonatal growth plate is incomplete, especially concerning biochemical changes. This study was designed to explore the cellular and biochemical responses of the cranial base growth plate (CBGP) explant upon cyclic loading. The growth plate with subchondral bone was as...

In the published literature there are controversial data to the biomechanical stability of monocortical comparing to the bicortical fixation of metacarpal fractures. The aim of this study was to compare the biomechanical stability of monocortical and bicortical locking osteosynthesis in quasi-static and dynamic 4-point bending tests of composite third metacarpal bone (4th Gen third metacarpal, ...

pistacia vera l., a member of anacardiaceae family, has been used for sedation and analgesia in traditional medicine. in this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of p. vera leaves were investigated in mice. the antinociceptive activity was studied using hot plate and writhing tests. the effect of the extracts a...

We apply a nonlinear-nonlocal field theory for numerical calculation of quasistatic fracture. The model is given by regularized nonlinear pairwise potential in peridynamic formulation. function an explicit formula with first and second derivatives. This fact allows us to write the entries tangent stiffness matrix explicitly thereby saving computational costs during assembly matrix. validate our...

OBJECTIVES The aim of the present study was to develop a plate to treat mandibular angle fractures using the finite element method and mechanical testing. MATERIAL AND METHODS A three-dimensional model of a fractured mandible was generated using Rhinoceros 4.0 software. The models were exported to ANSYS(®), in which a static application of displacement (3 mm) was performed in the first molar ...

This paper summarizes the experimental campaign carried out for development of new steel energy dissipative devices named Slit Dampers (SDs) designed earthquake protection structures. A total eighty-two shear plates with different openings and thicknesses are tested to investigate their behaviour under cyclic pseudo-static loading. Eight types studied, including SD narrow slits that divide plat...

Progress Using mathematical models, we are investigating the influence of plate fixation on the internal stresses in long bones subjected to all known in vivo loading modes . The variables we are studying include : plate geometry, plate/bone fixity, and screw tightness. The mathematical models are based upon the finite element technique . The models will be subjected to all physiological loadin...

Different calcaneal plates with locked screws were compared in an experimental model of a calcaneal fracture. Four plate models were tested, three with uniaxially-locked screws (Synthes, Newdeal, Darco), and one with polyaxially-locked screws (90 degrees +/- 15 degrees ) (Rimbus). Synthetic calcanei were osteotomised to create a fracture model and then fixed with the plates and screws. Seven sp...

A three-dimensional stress-concentration analysis was conducted on straight-shank and countersunk (rivet) holes in a large plate subjected to various loading conditions. Three-dimensional nite-element analyses were performed with 20-node isoparametric elements. The plate material was assumed to be linear elastic and isotropic, with a Poisson's ratio of 0.3. Stress concentrations along the bore ...