background autologous platelet concentrate has been used to improve the function and regeneration of injured tissues. tendinopathies are common in clinical practice, although long-term treatment is required. on the basis of lead time, we compared the effect of using platelet-rich plasma (prp) and platelet-rich fibrin (prf) in repairing rat achilles tendon. methods the effectiveness of using prp...

background: the purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (prp) and platelet-rich fibrin (prf) containing stromal cell-derived factor-1 (sdf1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect. methods: we created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen mat...

abstract background autologus platelet gel is easy to prepare and is relatively low cost. the aim of this study was to prepare and evaluate in vitro efficacy of autologus platelet gel. materials and methods in this experimental study, platelet concentrate and platelet poor plasma were prepared with aphaeresis method. thrombin was prepared by mixing the plasma with calcium. thrombin activity lev...

Background: Platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. Platelet concentrates can be prepared by the apheresis method or from the whole blood using the Buffy-coat or Platelet-rich plasma methods. The purpose of this study was to compare four variations of platelet-rich plasma method based on double...

Granulicatella adiacens is a catalase-negative, oxidase-negative, facultatively anaerobic, Gram-positive coccus [1]. This bacterium is considered nutritionally variant streptococci (NVS) because of its requirement for pyridoxal, L-cysteine, or additional nutrients, such as sulfhydryl compounds, for growth [2]. G. adiacens can grow well on culture medium containing these required nutrients. G. a...

Background: Immune thrombocytopenia is a hematologic disorder characterized by low platelet count and variable bleeding manifestations due to immune-mediated platelet destruction and/or suppression of platelet production. This study was performed to evaluate characteristics and clinical presentations of adult patients with immune thrombocytopenia and to explore the clinical value of platelet an...

Blood transfusion centers are under considerable pressure to produce platelet concentrates with a shelf life limit of 3 to 5 days. Many approaches have been investigated experimentally to produce new hemostatically active platelet products that are capable of long term storage. In this article infusible platelet membrane will be explained as a platelet substitute versus conventional liquid-stor...

blood transfusion centers are under considerable pressure to produce platelet concentrates with high quality and safety due to the short shelf life of 3-5 days as well as possible bacterial and viral contaminations. for a variety of reasons, many europeans have changed their methods of component production from whole blood using the north american standard platelet-rich plasma method to the buf...

background: activated platelets shed microparticles (mps) in vivo and certainly in vitro under storage. like platelets, platelet-derived mps contribute to hemostatic and inflammatory responses. we sought to determine the interactions between platelet mps and peripheral b lymphocytes in the healthy blood circulation to propose a possible role for platelet mps in the functioning of b cells.   mat...

Abstract Background Autologus platelet gel is easy to prepare and is relatively low cost. The aim of this study was to prepare and evaluate in vitro efficacy of autologus platelet gel. Materials and Methods In this experimental study, platelet concentrate and platelet poor plasma were prepared with aphaeresis method. Thrombin was prepared by mixing the plasma with calcium. Thrombin activity...