Platinum metal catalyzes the reduction of dialkyl(diolefin)platinum(II) complexes by dihydrogen to alkanes and platinum(0). The reaction involves adsorption of the platinum(II) complex on the platinum(0) catalyst surface with conversion of the alkyl moieties to platinum surface alkyls; these appear as alkane products. The platinum atom originally present in the soluble organoplatinum species be...

background : the brain is a rare site of metastases from ovarian cancer. limited data are available on prognostic factors, standard treatment, and survival. knowledge of clinical prognostic factors would help the management of patients with brain metastases. the aim of this study is to evaluate the impact of clinical factors and treatment modalities on survival in patients with brain metastases...

BACKGROUND Ovarian cancer is the fifth most common cancer in the UK, and the fourth most common cause of cancer death. Of those people successfully treated with first-line chemotherapy, 55-75% will relapse within 2 years. At this time, it is uncertain which chemotherapy regimen is more clinically effective and cost-effective for the treatment of recurrent, advanced ovarian cancer. OBJECTIVES ...

OBJECTIVES Assessment of level of exposure to platinum and platinum concentration in urine from platinum industry workers to evaluate internal exposures and excretion kinetics. METHODS Platinum concentrations in urine samples from 34 workers were measured by adsorptive voltammetry after UV-photolysis. Morning and evening samples were taken two to six times during six months. Individual exposu...

Flow-Through Catalysts for Diesel Engine Emissions Control Royal Commission Report on Diesel Emissions Chemical Reaction Fronts on Platinum Surfaces Platinum Catalyses the Conversion of Methane to Higher Alkanes Metal-Hydrogen Systems The Plastic Flow of Iridium Ammonia Sensor Uses Platinum Films Partners in Innovation Conference Recovery of Platinum Group Metals from High Level Radioactive Was...

BACKGROUND The aim of this study was to evaluate long-term platinum retention in patients treated with cisplatin and oxaliplatin. METHODS 45 patients, treated 8-75 months before participating in this study, were included. Platinum levels in plasma and plasma ultrafiltrate (pUF) were determined. In addition, the reactivity of platinum species in pUF was evaluated. Relationships between platinu...

The effectiveness of platinum re-treatment in relapsed ovarian cancer depends on relapse-free/treatment-free intervals. Platinum agents can be effectively readministered to platinum-sensitive patients (relapsing >12 months after platinum), but efficacy is lower in partially platinum-sensitive (PPS) disease (relapsing 6-12 months after platinum). There is no clear standard treatment challenging ...