Objective Anti-Rh D IgG is used for the prevention of anti-D antibody production in Rh- individuals who have been exposed to Rh+ red blood cells. The stability of IgG preparations as a solution is low, with a shelf life of a year or more. Formulation of anti-Rh D IgG as a lyophilized preparation would decrease its degradation rate and increases its shelf life. The objective of this study was t...

Abstract Uncertainty in climate feedbacks is the primary source of spread projected surface temperature responses to anthropogenic forcing. Cloud feedback persistently appears as main disagreement future projections while combined lapse‐rate plus water vapor (LR + WV) a smaller (30%), but non‐trivial uncertainty sensitivity. Here we attempt observationally constrain an effort reduce their inter...

Background: This paper presents a method to reduce radiation exposure during mammography by analysing the doses to ipsilateral and contralateral breasts and to adjacent organs by evaluating material-dependent shielding performance.  Materials and Methods: Six target-filter combinations (Mo-Mo, Mo-Rh, Rh-Rh, Rh-Mo, W-Mo, W-Rh) were tested by measuring the doses delivered to the breasts and adjac...

BACKGROUND Minocycline and a non-steroidal anti-inflammatory drug (NSAID) indomethacin, have anti-inflammatory activities and are both used in the management of rheumatoid arthritis. However, there are no reports on whether coadministration of these drugs could potentiate each other's activities in alleviating pain and weight bearing deficits during arthritis. METHODS LPS was injected to BALB...

Antitumoral effects of the agonist of luteinizing hormone-releasing hormone (p-Trp-6-LH-RH) and the somatostatin analog RC-160 (D-PheCys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH:) on chemically induced ductal pancreatic adenocarcinomas were studied. The tumors were induced in female Syrian golden hamsters by weekly s.c. injections of /V-nitrosobis(2oxopropv Damine at a dose of 10 mg/kg b.w. for 6 weeks. 18...

We employed intracoronary infusions of calf intestine adenosine deaminase (ADA) to test the hypothesis that adenosine regulates coronary blood flow during myocardial reactive hyperemia (RH). Infusions of 4.5 U ADA/min per kg body weight into the left circumflex coronary artery of 10 open-chest dogs reversibly reduced repayment of flow debt by 30-39% (P less than 0.05) following 5-, 10-, 15-, 20...

The application of the biocontrol agent Pantoea agglomerans EPS125 to unwounded fruits was practically ineffective for control of postharvest blue mould caused by Penicillium expansum when the treatment and subsequent wounding and pathogen inoculation were separated by periods of unfavourable conditions. This was due to a rapid decrease in viability of the alocthonous introduced biocontrol agen...

Interactions of CD47 and RhAG and the Rh proteins are visualized between one another and with the cytoskeleton of intact erythrocytes. In a first study, CD47 is labeled with a phycoerythrin (PhE)– tagged antibody, which generates discrete spots that reflect induced clusters of CD47. Rh and RhAG colocalize with each other and to these induced clusters, whereas Band 3 and glycophorin C remain mor...

This study investigated whether recombinant human soluble Fas ligand (rh-sFasL) induces apoptosis of primary type II pneumocytes in vitro and lung injury in vivo. Type II cells isolated from normal rabbit lung expressed Fas on their surface and became apoptotic after an 18-h incubation with rh-sFasL. Fas expression in normal rabbit lungs was localized by immunohistochemistry to alveolar and air...

Abstract R-parity conserving supersymmetric models with right-handed (RH) neutrinos are very appealing since they could naturally explain neutrino physics and also provide a good dark matter (DM) candidate such as the lightest particle (LSP). In this work we consider next-to-minimal standard model (NMSSM) plus RH superfields, effective Majorana masses dynamically generated at electroweak scale ...