1. Adult rhesus monkeys possess frequently a greater resistance to experimental infection with poliomyelitis virus than young monkeys as indicated by the prolongation of the incubation period and the content of feeble neutralizing substances in the normal serum. 2. Virucidal substances can be demonstrated in the normal serum of subadult chimpanzees. 3. Immature monkeys prepared with glandular a...

Poliomyelitis (Heine-Medin disease) T he recent death of FC Robbins 1 , Nobel laureate and pioneer worker who cultivated the poliomyelitis virus, prompts this note. Poliomyelitis pre-dates recorded history. 2 Biblical descriptions of the lame and crippled lack sufficient detail for diagnosis. However, a funereal stele of the priest Ruma from the 19th Egyptian dynasty shows shortening and marked...

Paralytic poliomyelitis has been nationally notifiable in Canada since 1924. The last case of indigenous wild paralytic poliomyelitis in Canada occurred in 1977, and Canada, along with the rest of the American Region, was formally certified as polio-free by the International Commission for the Certification of Poliomyelitis Eradication in September 1994(1). Despite the elimination of indigenous...

conclusions health managers in iran should continuously monitor the coverage of vaccination with at least three doses of opv in the level of over 95%, monitor the health of the helmand river water which comes from afghanistan to iran, vaccinate the immigrants and replace bivalent vaccine (bopv) with trivalent (topv) vaccine. context the wild polio virus is disrupted in all countries in the worl...

Poliomyelitis virus and Coxsackie (or C) virus were quantitatively fed to blowflies, Phormia regina and Phaenicia sericata, and to houseflies, Musca domestica. Naturally infectious human stools were the source of virus. Poliomyelitis virus can be almost quantitatively recovered from flies and from their excreta collected over a period of several days following the feeding. C virus can also be r...

This volume contains the twenty-six papers and the discussions which followed them as well as the twenty exhibits presented at the Third International Poliomyelitis Conference in Rome in 1954. The field was covered under the headings: Social Aspects, Acute Medical Care, Infection and Immunity, Developments in Tissue Culture, Orthopedics, Physical Medicine and Rehabilitation, and, finally, Trend...

1. Cynomolgus monkeys were subjected to a series of non-traumatic exposures of the mucous membranes of the alimentary tract, designed to test the relative permeability to poliomyelitis virus of its upper and lower portions. 2. In the first stage, dried poliomyelitis virus of tested potency was administered in fat-covered capsules to 26 monkeys in such a way as to avoid contamination of the orop...

Examination of 50 autopsied cases of human poliomyelitis showed prominent hyperplastic and inflammatory changes in the lymphoid tissues of 41, the most frequent and severe lesions observed save those in the central nervous system. Histologically the germinal centers showed prominent degenerative and regenerative alterations, fluid transudation, giant cell formation, and rare inclusion bodies, a...

It is a special pleasure for me to contribute something, even something so meager as the present communication, to the number of the Yale Journal of Biology and Medicine issued in honor of John R. Paul. It is 30 years since we first met and began, each in his own way, to study certain aspects of poliomyelitis. Together we have passed through an exciting era in the development of knowledge of th...