Author's View CD8 + cytotoxic T lymphocytes (CTLs) are the most efficient mediators of the adaptive immune system. Among the myriad of immune cell responses to cancer, CTLs are capable of both recognizing and destroying tumor cells. CTLs recognize antigens on the surface of tumor cells that are presented as MHC class I-peptide complexes. These peptides, known as CTL epitopes, are commonly deriv...

A voltage-controlled oscillator (VCO) based analogto-digital converter (ADC) utilizing Sigma-Delta (Σ−Δ) techniques for second order quantization noise shaping is presented. A custom IC prototype of this highly digital architecture achieves 60-dB signal-to-noise ratio (SNR) over a 1-MHz bandwidth with 800-MHz sampling rate. It was fabricated in a 0.18-μm 1-poly 5-metal CMOS technology.

BACKGROUND Clinical studies showed the contribution of viral infection to the development of asthma. Although mast cells have multiple roles in the pathogenesis of allergic asthma, their role of in the virus-associated pathogenesis of asthma remains unknown. Most respiratory viruses generate double-stranded (ds) RNA during their replication. dsRNA provokes innate immune responses. We recently s...

A design method of low-pass (LP) negative group delay (NGD) integrated circuit (IC) implemented in 130-nm BiCMOS technology is investigated. The LP-NGD composed by RL-network with high Ohmic unsalicided N+poly resistor and symmetrical current spiral inductor. methodology the investigated explained chip layout process. Then, pre-simulation performed rule check (DRC) 225 μm × 215 versus schematic...

a-Tocopherol (a-TC) and a-TC/cyclodextrin (CD)–inclusion complex (IC) incorporated electrospun poly(lactic acid) (PLA) nanofibers (NF) were developed via electrospinning (PLA/a-TC–NF and PLA/a-TC/g-CD–IC–NF). The release of a-TC into 95% ethanol (fatty food simulant) was much greater from PLA/a-TC/g-CD–IC–NF than from PLA/a-TC–NF because of the solubility increase in a-TC; this was confirmed by...

Suitable electro-catalytic technique is established for the selective determination of Indigo Carmine (IC) at poly(arginine) modified carbon paste electrode (PAMCPE). The surface morphological study done through Field Emission Scanning Electron Microscopy (FESEM). different parameters such as concentration, pH and scan rate on response are studied. individual simultaneous performance IC Ribofla...

A series of supramolecular aggregates were prepared using a poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) (PPO-PEO-PPO) block copolymer and β- or α-cyclodextrins (CD). The combination of β-CD and the copolymer yields inclusion complexes (IC) with polypseudorotaxane structures. These are formed by complexation of the PPO blocks with β-CD molecules producing a powder precipitat...