BACKGROUND Hill and valley scarring is 1 of 3 atrophic scar types that occur as a result of acne, becoming more apparent with facial skin aging. Treatment includes resurfacing techniques and the use of injectable fillers. Poly-L-lactic acid is an injectable collagen builder that has been used for the treatment of HIV-associated lipodystrophy and cosmetic enhancement. OBJECTIVE To determine th...

INTRODUCTION Poly-L-lactic acid (Sculptra, Sanofi Aventis, Bridgewater, NJ) is a gel polymer made of poly-Llactic acid microspheres and water suspended in a mannitol and carboxymethyl cellulose suspension. This injectable tissue filler has been used for correction of lipoatrophy in HIV patients as well as for cosmetic purposes since its US Food and Drug Administration approval in 2004. The mech...

The synthesis and characterization of two homoleptic Zn(II)- Mg(II)-complexes based on a simple tridentate {NNO} ligand are reported. production biocompatible atactic poly(lactic acid) (...

Imine-containing bridging groups were formed during self-assembly of periodic mesoporous organosilicas by in situ dynamic covalent chemistry of aldehyde and amine groups in the presence of poly(ethylene oxide)-poly(dl-lactic acid-co-glycolic acid)-poly(ethylene oxide) block copolymer in acidic aqueous solutions.

BACKGROUND A thermal tolerant stereo-complex poly-lactic acid (SC-PLA) can be made by mixing Poly-D-lactic acid (PDLA) and poly-L-lactic acid (PLLA) at a defined ratio. This environmentally friendly biodegradable polymer could replace traditional recalcitrant petroleum-based plastics. To achieve this goal, however, it is imperative to produce optically pure lactic acid isomers using a cost-effe...

Polymeric biomaterials are used as substitutes for damaged tissue and for the stimulation of tissue regeneration. One class of polymeric biomaterials are bioresorbable polymers that degrade both in vitro and in vivo and are used as a temporary support for tissue regeneration. Among the various types of bioresorbable polymers, -hydroxy acids including the different forms of poly(lactic acid) (P...

Novel therapies are crucially needed for short bowel syndrome. One potential therapy is the production of tissue engineered intestine (TEI). The intestinal environment presents significant challenges to the selection of appropriate material for tissue engineering scaffolds. Our goal was to characterize different scaffold materials to downselect to that best suited for TEI production. To investi...

Electrospun scaffolds can find numerous applications, including biomedical; for example, tissue engineering. Poly-L-lactic acid is considered suitable these but its low-thermal stability and poor mechanical properties limit this polymer use. The aim of work to obtain a modulation the final characteristics such as fibers dimension, wettability, elasticity, resistance rupture through choice polym...

Starch- graft -poly(lactic acid) is put forward as an efficient compatibilizer of thermoplastic starch – PLA binary blend for a sustainable and high barrier film structures.