PURPOSE Dexmedetomidine, a potent selective α2-adrenergic agonist, produces sedation and analgesia. This study was conducted to assess the effect of dexmedetomidine infusion on sevoflurane requirements, recovery profiles, and emergence agitation in children undergoing ambulatory surgery. MATERIALS AND METHODS Forty children undergoing ambulatory hernioplasty or orchiopexy were randomized into...

Effect of ketamine versus alfentanil following midazolam in preventing emergence agitation in children after sevoflurane anaesthesia: A prospective random-ized clinical trial. Ketamine is effective in decreasing the incidence of emergence agitation in children undergoing dental repair under sevo-flurane general anesthesia. Effects of ketamine and midazolam on emergence agitation after sevoflura...

BACKGROUND Opioids are generally the preferred analgesic agents during the early postoperative period. OBJECTIVES The present study was designed to assess and compare the multimodal analgesic effects of ketamine and tramadol in combination with intravenous acetaminophen after renal surgery. PATIENTS AND METHODS This randomized, double-blinded, clinical trial was conducted on 80 consecutive ...

A 6 year old boy developed hyperammonaemic encephalopathy following a subureteric injection for treatment of vesicoureteric reflux. The hyperammonaemia may be explained by a postoperative urinary tract infection with a urea splitting organism, leading to raised urine ammonia that was absorbed easily across a dilated urinary tract. Agitation and alteration in consciousness level following a urol...

conclusions according to the results of the current study, postoperative analgesia in children was improved in the ketamine group. therefore, for better management of posttonsillectomy pain, low-dose ketamine administration with paracetamol is recommended. results there was no significant difference between the two groups considering demographic data (age, sex distribution, weight and height). ...

OBJECTIVE OF THE STUDY to analyze the efficiency and safety of Dexmedetomidine infusion for a short-term controlled sedation and treatment of delirium in the early postoperative period in patients after cardiac surgery. METHODS open, randomized, prospective study of 28 patients undergoing surgery on the heart or main blood vessels under general anaesthesia. In the early postoperative period a...