Prangos ferulacea is a plant found in the Mediterranean and Middle-east regions used as carminative, anti-flatulent, emollient and antibacterial herb. It is believed that the coumarins are responsible for some of known effects of Prangos. In this research the relaxant effects of P. ferulacea coumrin rich extract as well as osthole as its main prenylated coumarins were investigated on rat ileum ...

coumarins are bioactive secondary metabolites and could be found in the fruits of umbelliferae. prangos asperula boiss. is an iranian native plant which is found wild in many regions of iran. osthol, a prenylated coumarin, was isolated from the hexane extract of the fruits of p. asperula and its structure was elucidated using 1 hnmr, 13 cnmr, ir and ms spectra. the essential oil of the aerial p...

Inhibition of the cell growth or induction of cell death is the most promising area in cancer therapy. The induction of apoptosis by dichloromethane extract of Prangos uloptera was evaluated on the McCoy cell line. This plant's roots, aerial parts and fruit have medicinal value. Cell growth inhibitory and cell cytotoxicity effects of the extract were assayed by MTT and Trypan-blue tests, respec...

prangos ferulacea (l.) lindl. (apiaceae) is a medicinal plant distributed in mediterranean regions, caucasia and southwest of asia. in the present study phytochemical constituents of the extract obtained from the aerial parts of p. ferulacea were investigated using various chromatographic and spectroscopic methods. essential oil of the plant aerial parts was also analyzed using gc-ms. five phen...