Drosophila Polycomb group response elements (PRE) silence neighboring genes, but silencing can be blocked by one copy of the Su(Hw) insulator element. We show here that Polycomb group (PcG) proteins can spread from a PRE in the flanking chromatin region and that PRE blocking depends on a physical barrier established by the insulator to PcG protein spreading. On the other hand, PRE-mediated sile...

A series of Saccharomyces cerevisiae--Escherichia coli shuttle vectors is described in which small RNAs can be stably expressed in yeast from two different promoters for RNA polymerase III transcription. The vectors are available in either high- or low-copy-number forms with either URA3, HIS3, or TRP1 selection markers, and are based on a previously described set of plasmid vectors [Sikorski an...

Pre-reassociation of human clone probes, containing dispersed highly repeated sequences, (e.g. Alu and KpnI families), with a large excess of sonicated total human DNA allows signal from single and low copy number components to be detected in transfer hybridisations. The signal from non-dispersed repeated sequences is reduced to single copy levels. The procedure, which is simple and quick, is i...

Due to the scalability and flexibility in power transmission, the Modular Multilevel Converter (MMC) receives a widespread favor since its advent. The popularization of the MMC will continuously promote the developments in renewable energy grid connecting and flexible High Voltage Direct Current transmission (HVDC) system. In this paper, an overview of the most recent effort associated with the...

Approach we have tested in our submitted runs. Our approach consists in finding links between video shot key-frames, based on the use of a probabilistic latent space model over local matches between the keyframe images. This allows the extraction of significant groups of local matching descriptors that may represent common characteristic elements of near duplicate key-frames. This is combined w...

in the name of God, most gracious, most merciful Physiology and Pharmacology Indexing: Index Copernicus (IC), Scientific Information Database (SID) Physiology and Pharmacology is the official publication of the Iranian Society of Physiology and Pharmacology. The journal publishes full-length original articles in physiology, pharmacology and related subjects. Editorial office: ...

This study is an experimental that aims to determine the effectiveness of use copy master learning techniques in write explanation texts class XI-IPS SMA Negeri 14 Maluku Tengah. The research data were form results text writing test which taken from pre-test and post-test control class. subjects students Makuku Tengah, totaling 42 people. final score each student obtained number correct answers...

Cellular heterogeneity plays a pivotal role in a variety of functional processes in vivo including carcinogenesis. However, our knowledge about cell-to-cell diversity and how differences in individual cells manifest in alterations at the population level remains very limited mainly due to the lack of appropriate tools enabling studies at the single-cell level. We present a study on changes in c...

Copy-move forgery is the most popular and simplest image manipulation method. In this type of forgery, an area from the image copied, then after post processing such as rotation and scaling, placed on the destination. The goal of Copy-move forgery is to hide or duplicate one or more objects in the image. Key-point based Copy-move forgery detection methods have five main steps: preprocessing, fe...

Alzheimer's disease (AD) is the major cause of adult-onset dementia and is characterized in its pre-diagnostic stage by reduced cerebral cortical glucose metabolism and in later stages by reduced cortical oxygen uptake, implying reduced mitochondrial respiration. Using quantitative PCR we determined the mitochondrial DNA (mtDNA) gene copy numbers from multiple groups of 15 or 20 pyramidal neuro...