Objective: The study's objective involved compatibility studies to investigate the possible interactions between 5-fluorouracil (5-FU) and four different lipids, most appropriate lipid was chosen. Differential scanning calorimetry (DSC), X-ray diffraction (XRD), Fourier Transform Infrared spectroscopy (FT-IR) are used for study 5-FU several excipients as cholesterol, compritol®, stearic acid, g...

BACKGROUND Chemo/radio-resistance is a major obstacle in treating advanced ovarian cancer. The efficacy of current treatments may be improved by increasing the sensitivity of cancer cells to chemo/radiation therapies. Curcumin is a naturally occurring compound with anti-cancer activity in multiple cancers; however, its chemo/radio-sensitizing potential is not well studied in ovarian cancer. Her...

Analysis of pre onditioners for saddle-point problems D. Loghin and A. J. Wathen Mixed nite element formulations give rise to large, sparse, blo k linear systems of equations the solution of whi h is often sought via a pre onditioned iterative te hnique. In this work we present a general analysis of blo kpre onditioners based on the stability onditions inherited from the formulation of the nite...

This paper questions the influence of a pre-existing information technology (IT) infrastructure on the formulation of an organizational knowledge strategy. We draw on a classification of four different strategic views of IT infrastructure and explore how the historic investment in IT infrastructure enables and constrains the formulation of knowledge strategy in four case organizations. The four...