The overabundance of heavy nuclei in solar cosmic rays of energy < 5 Mev/nucleon is explained by taking into account the pre-flare ionization states of these nuclei in the region where they are accelerated. A model is proposed which considers two-step accelerations associated with the initial development of solar flares. The first step is closely related to the triggering process of flares, whi...

We developed a modified paper spray ionization (PSI) platform, named as paper cone spray ionization (PCSI), for direct mass spectrometric analysis of raw solid samples. The major modification from conventional PSI was the geometry of the paper base: PCSI uses a triangular-pyramidal-shaped paper tip instead of a planar triangular-shaped one. This three-dimensional paper cone serves as a sample c...

We develop a consistent model of the accretion shock region in Classical T Tauri Stars (CTTSs). The initial conditions of the post-shock flow are determined by the irradiated shock precursor and the ionization state is calculated without assuming ionization equilibrium. Comparison with observations of the C IV resonance lines (λλ 1550 Å) for CTTSs indicate that the post-shock emission predicted...

Doping via self-assembled macromolecules might offer a solution for developing single atom electronics by precisely placing individual dopants at arbitrary location to meet the requirement for circuit design. Here we synthesize dendrimer-like polyglycerol macromolecules with each carrying one phosphorus atom in the core. The macromolecules are immobilized by the coupling reagent onto silicon su...

A reference monoclonal antibody IgG1 and a fusion IgG protein were analyzed by top- and middle-down mass spectrometry with multiple fragmentation techniques including electron transfer dissociation (ETD) and matrix-assisted laser desorption ionization in-source decay (MALDI-ISD) to investigate heterogeneity of glycosylated protein species. Specifically, glycan structure, sites, relative abundan...

A method is described for the qualitative and semi-quantitative simultaneous determination of both non-macrocyclic and macrocyclic trichothecene biotoxins from samples derived from indoor environments. The method includes extraction, sample pre-treatment and reversed-phase HPLC separation followed by tandem mass spectrometric identification and quantification using electrospray ionization on a ...

Cardinal is an R package for statistical analysis of mass spectrometry-based imaging (MSI) experiments of biological samples such as tissues. Cardinal supports both Matrix-Assisted Laser Desorption/Ionization (MALDI) and Desorption Electrospray Ionization-based MSI workflows, and experiments with multiple tissues and complex designs. The main analytical functionalities include (1) image segment...

in this paper, we calculate electron and hole impactionization coefficients in in0.52al0.48as using a monte carlo modelwhich has two valleys and two bands for electrons and holesrespectively. also, we calculate multiplication factor for electronand hole initiated multiplication regimes and breakdown voltagein in0.52al0.48as pin avalanche photodiodes. to validate themodel, we compare our simulat...

The triggering and guiding of the stationary high voltage (HV) discharges at 5-40 kV are demonstrated by using plasma filaments generated by single and dual femtosecond(fs) laser pulses in air. A significant reduction of the breakdown voltage threshold due to the pre-ionization of the air gap by laser pulse filamentaion was observed. The amount of free electrons of filaments generated by differ...