Mole fraction solubilities of tadalafil (3) in aqueous mixtures Transcutol® and PEG 400 at temperatures from 298.15 to 333.15 K were analysed following Hildebrand solubility parameters. Cosolvency models for representing various also provided correlation/prediction purposes. Apparent thermodynamic quantities dissolution processes calculated based on van’t Hoff Gibbs equations. Non-linear enthal...

Typically agents have obligations of diiering importance. Consequently we give a hierarchical deenition of obligations, according to which an agent's obligations form a coherent hierarchy and new obligations are de-ned with reference to it. We then show how preferential entailment can be used to formalise the persistence and revision of obligation hierarchies.

Background: Cisplatin is an antineoplastic agent used to treat many malignancies; however, the main side effect of cisplatin is nephrotoxicity. The aim of this study was to evaluate the effect of hydration therapy with and without magnesium on prevention of cisplatin-induced nephrotoxicity. Methods: This retrospective study was performed on 46 patients with malignancy who were candidate to rec...

This article addresses the interplay between heat of hydration and physico-mechanical properties of calcium sulfate hemi-hydrate in the presence of retarding additives such as citric and malic acids and sodium citrate. The heat of hydration was measured using a semi-isothermal calorimeter. Results proved that citric and malic acids had superior impact on hydration and mechanical properties. Whi...

Mechanical systems, of the kinds which are of interest for qualitative reasoning, are characterized by a set of real-valued parameters, each of which is a piecewise continuous function of real-valued time. A temporal logic is introduced which allows the description of parameters, both in their continuous intervals and around their breakpoints, and which also allows the description of actions be...

Modelling the beliefs of an agent who lacks logical omniscience has been a major concern recently. While most of the work has concentrated on propositional logics of belief, this paper primarily addresses issues raised by adding quantifiers to such logics. In particular, we are focusing on quantifying in and the distinction between "knowing what" and "knowing that". After arguing why a model of...

In this paper we introduce and formalise dynamic goal hierarchies. We begin with a formal definition of goals, according to which they are rational desires. In particular, we require that an agent’s goals are coherent; that is, that the agent believes that each goal is jointly realisable with all of the goals which the agent considers to be more important. Thus an agent’s goals form a hierarchy...

This memo presents current research in our laboratory. We address the following research topics: 1. Semantics-based assessment of nonmonotonic entailment methods for actions and change. 2. Implementation techniques for nonmonotonic entailment methods. 3. Algorithmic methods for planning and temporal reasoning. 4. Hybrid modelling of physical systems. 5. Design methodology for intelligent autono...

abstract eating and drinking are essential for life. there are clinical situations that artificial hydration is necessary. for dying patients artificial hydration looks useless and in many conditions could even be harmful (e.g. pulmonary edema in hypoalbuminemic patients). in our medical culture artificial hydration is a symbol of care to the patient and withholding it, is a very emotive issue,...

this article addresses the interplay between heat of hydration and physico-mechanical properties of calcium sulfate hemi-hydrate in the presence of retarding additives such as citric and malic acids and sodium citrate. the heat of hydration was measured using a semi-isothermal calorimeter. results proved that citric and malic acids had superior impact on hydration and mechanical properties. whi...