background:   objective: to investigate the effectiveness of levothyroxine in treatment of rpl in women with high auto-thyroid antibodies.   materials and methods: in this observational cross sectional study, 900 women who had a history of recurrent pregnancy loss were studied. all women with high anti-tpo antibody without any other problems entered in this study. levothyroxine was given to the...

Background Recurrent pregnancy loss (RPL) is usually defined as three or more consecutive pregnancy losses before 20th gestational week. Many etiological factors have been considered as cause of RPL including genetic factors, uterine anatomical defects, endocrine abnormalities, thrombotic and immunologic factors. Nevertheless, the cause of RPL remains unknown in around half of the patients desp...

OBJECTIVE To study the relationship between semen quality and pregnancy loss in a cohort of couples attempting to conceive. DESIGN Observational prospective cohort. SETTING Not applicable. PATIENT(S) Three hundred and forty-four couples with a singleton pregnancy observed daily through 7 postconception weeks of gestation. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Association betwe...

Background: Recurrent pregnancy loss (RPL) is a common and distressing disorder. RPL is a devastating reproductive problem affecting approximately 5% of couples trying to conceive. If we camper the rate of miscarriage in couples may experience RPL with the pregnancy loss rate in general population we may calculate that it is at least two or three times higher than expected. This study aimed to ...

Spontaneous abortion is the most common complication of pregnancy. Several lines of evidence indicate that immunologic effector cells may play a role in the pathogenesis of idiopathic repetitive abortions. Leukocytes form a substantial proportion of stromal cells in decidua and the endometrial granulated lymphocytes (eGL) is the predominant decidual leukocyte population in the first trimester o...