supplementation and childhood morbidity from diarrhea and respiratory infections: A meta-analysis. The beneficial effects of weekly low-dose vitamin A supplementation on acute lower respiratory infections and diarrhea in Ecuadorian children. Double blind, cluster rando-mised trial of low dose supplementation with vitamin A or beta carotene on mortality related to pregnancy in Nepal. The Nnips-2...

BACKGROUND Anemia in pregnancy is highly prevalent among antenatal clinic attendees in Enugu, Nigeria despite the practice of routine iron supplementation in pregnancy. The major problem with iron supplementation in pregnancy is compliance, and this may be a potential driver to the persistent high prevalence of anemia in this population. OBJECTIVES To find out the compliance rate and determin...

Background: High maternal hemoglobin concentration has been increasingly linked to poor pregnancy outcomes in recent years. This study was aimed to determine whether high maternal hemoglobin (Hb) in first trimester is associated with preeclampsia. Materials and Methods: In 2009 a retrospective study was conducted and demographic and obstetric records of 1513 low risk pregnant mother registered ...

BACKGROUND Calcium supplementation during pregnancy may prevent high blood pressure and preterm labour. OBJECTIVE To assess the effects of calcium supplementation during pregnancy on hypertensive disorders of pregnancy and related maternal and child adverse outcomes. DESIGN A systematic review of randomised trials that compared supplementation with at least 1 g calcium daily during pregnanc...

Background: Low plasma folate concentrations in pregnancy are associated with preterm birth. Here we show an association between preconceptional folate supplementation and the risk of spontaneous preterm birth. Methods and Findings: In a cohort of 34,480 low-risk singleton pregnancies enrolled in a study of aneuploidy risk, preconceptional folate supplementation was prospectively recorded in th...

To the Editor: In summarizing their well-executed randomized trial, Progesterone in Recurrent Miscarriages (PROMISE), Coomarasamy et al. (Nov. 26 issue)1 state that there is no evidence of benefit from progesterone supplementation “in the first trimester” of pregnancy among women who have had three or more miscarriages. We wish to clarify three points. First, the trial did not address progester...

INTRODUCTION Approximately 60-70 pregnancies are affected by neural tube defects (NTD) in Denmark annually. Folic acid (FA) deficiency can cause NTD. Periconceptional FA supplementation reduces the risk of NTD by up to 70-80%. Danish women planning pregnancy are recommended 0.4 mg of FA daily from at least one month before planned conception and continuing throughout the first 12 weeks of pregn...