OBJECTIVE To quantify an apparent nasotemporal asymmetry in the location of retinopathy of prematurity with respect to the optic disc. METHODS Twenty-four-bit color images were captured using a contact digital fundus camera during routine screening. Semiautomated measurements were undertaken to determine the distance between the optic disc and retinopathy located in the nasal and temporal reg...

Background: Eye examination for screening of Retinopathy of Prematurity (ROP), as a painful procedure, causes physiological changes in premature infants. Multisensory stimulation is a non-pharmacological analgesic method which affects physiological measures during painful procedures. Aim: To determine the effect of multisensory stimulation on oxygen saturation in premature infants during eye ex...

Background: The aim of the study was to compare functional and structural outcomes of treatment for retinopathy of prematurity with diode laser photocoagulation and cryotherapy. Materials and methods: We examined 111 children aged 4 years, treated for retinopathy of prematurity by transpupillary diode laser photocoagulation or cryotherapy. Both functional (visual acuity, orthoptic status) and s...

AIMS Ischemic retinal diseases such as retinopathy of prematurity are major causes of blindness due to damage to the retinal microvasculature. Despite this clinical situation, retinopathy of prematurity is mechanistically poorly understood. Therefore, effective preventative therapies are not available. However, hypoxic-induced increases in reactive oxygen species (ROS) have been suggested to be...

PURPOSE To investigate the efficacy of intravitreal injection of anti-vascular endothelial growth factor agents for Stage 4 retinopathy of prematurity. METHODS Retrospective case series study. The medical records of patients receiving intravitreal injection of anti-vascular endothelial growth factor agents for Stage 4 retinopathy of prematurity from January 2007 to May 2012 in Taipei Veterans...

OBJECTIVE Control of visual loss from retinopathy of prematurity requires high quality neonatal care, and timely screening and treatment of sight-threatening disease. We assessed services for retinopathy of prematurity provided by ophthalmic training institutions in major Indian cities. METHODS Eleven cities were purposefully selected and eye-care facilities were evaluated using predefined cr...

PURPOSE To compare infant and retinopathy of prematurity (ROP) characteristics from 3 clinical studies conducted over a 27-year period in the United States. DESIGN Secondary analysis of results of 3 clinical studies. PARTICIPANTS Infants with birth weight (BW) <1251 g. METHODS Analysis of data from the Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) and Early Treatment for Retinopat...

PURPOSE Fibrovascular contraction and tractional retinal detachment (TRD) are recognized complications associated with the use of anti-vascular endothelial growth factor agents in vasoproliferative vitreoretinopathies. The authors characterize TRDs that developed after intravitreal bevacizumab or ranibizumab therapy for vascularly active retinopathy of prematurity. METHODS This is an internat...

BACKGROUND The optimal arterial oxygen saturation in the first weeks of life is unknown for immature newborn infants. OBJECTIVES To determine the effect of targeting high versus low oxygen saturation in the first weeks of life on the outcome of very low and extremely low birth weight infants. METHODS Randomized and observational studies were sought that compared the outcomes in babies with ...