We examined the effects of flow on lymphatic endothelial cells by using conventional cascade preparations of isolated coronary arteries without intact endothelium. The pressurized thoracic ducts were intraluminally perfused at a constant flow rate ranging from 0.5 to 2.0 ml/min. A linear relationship was observed between the flow rate and the normalized amount of relaxing substance(s) released ...

Pressurized elastic capsules arise at scales ranging from the 10 m diameter pressure vessels used to store propane at oil refineries to the microscopic polymeric capsules that may be used in drug delivery. Nature also makes extensive use of pressurized elastic capsules: plant cells, bacteria and fungi have stiff walls, which are subject to an internal turgor pressure. Here, we present theoretic...

Secondary lymphatic valves are essential for minimizing backflow of lymph and are presumed to gate passively according to the instantaneous trans-valve pressure gradient. We hypothesized that valve gating is also modulated by vessel distention, which could alter leaflet stiffness and coaptation. To test this hypothesis, we devised protocols to measure the small pressure gradients required to op...

Cerebrovascular reactivity to CO2 or hypotension was studied in vivo and in vitro [pressurized arteries (∼82 μm) and arterioles (∼30 μm)] at 1 h after mild controlled cortical impact (CCI) injury in rats. The cortical perfusion response [assessed using laser-Doppler flowmetry (LDF)] to altered CO2 was diminished (up to 81%) after mild CCI injury. The responses to CO2 alterations in arteries and...

OBJECTIVE We developed an in vitro model for vasospasm post subarachnoid hemorrhage that was suitable for investigating brain vessel autoregulation. We further investigated the effects of iodinated contrast medium on the vascular tone and the myogenic response of spastic cerebral vessels. METHOD We isolated and perfused the superior cerebellar arteries of rats. The vessels were pressurized an...

OBJECTIVE Overproduction of reactive oxygen species such as hydrogen peroxide (H2O2) has been implicated in various cardiovascular diseases. However, mechanism(s) underlying coronary vascular dysfunction induced by H2O2 is unclear. We studied the effect of H2O2 on dilation of coronary arterioles to endothelium-dependent and endothelium-independent agonists. METHODS AND RESULTS Porcine coronar...

We have reported that high-hydrostatic-pressure (HHP) technology is safe and useful for producing various kinds of decellularized tissue. However, the preparation of decellularized or inactivated skin using HHP has not been reported. The objective of this study was thus to prepare inactivated skin from human skin using HHP, and to explore the appropriate conditions of pressurization to inactiva...

pressurized injection operation means the pressurized injection of a liquid or solution into pore of a mass of soil or stone and/ or cavity between them and built structures. the injected mortar mustconstitute a soil and/ or jel- like matter inside the cavites, and/ or the operations of the injection must cause sedimentation of the solid matter suspending in these cavites. the primary purpose o...

introduction: nowadays, efficient use of scarce water resources is one of the government’s importantgoals for dealing sustainable development in the agricultural sector. in addition to optimal exploitation and using of surface and groundwater resources, choosing of efficient types of irrigation technologies is a very important factor in sustainable water resource management. this study tries to...

abstract the main purpose of this study was to determine farmers’ satisfaction towards pressurized irrigation systems in kermanshah province. this study used a mixed method design with descriptive correlation emphasis. a researcher made questionnaire was used to collect data. a random sample of 274 farmers who have been equipped with pressurized irrigation systems during the last three years pa...