BACKGROUND Preterm delivery is the most common cause of neonatal morbidity and mortality in the United States. There is evidence that cervicovaginal infection could predispose to preterm labor. This study explored a possible association of evidence of inflammation on an otherwise normal Papanicolaou smear obtained during pregnancy with subsequent preterm labor and preterm delivery. METHODS Us...

conclusions there is no statistically significant relationship between preterm delivery and type of sludge. results the prevalence of preterm delivery was 14/3%. the frequencies of term delivery in mothers with dense, light and no sludge were 78/6%, 82/1% and 96/4 % respectively, and for preterm delivery they were 21/4%, 17/9% and 3/6% respectively. but there was no statistically significant re...

introduction: preterm birth is still a major health problem throughout the world, which results in 75% of neonatal mortality. preterm labor not only inflicts financial and emotional distress, it may also lead to permanent disability. the present study was conducted to determine the related risk factors and preventive measures of preterm labor. methods: this retrospective cross-sectional study a...

background: there are strong evidences suggesting the secretion of different cytokines in cervical fluid during preterm labor. betamethasone is widely administered for several reasons in preterm conditions. objective: to investigate the possible effect of betamethasone on endocervical cytokine concentration of women at risk of preterm labor. methods: in a randomized clinical trial of 80 prime-g...

background while tocolytic therapy can halt the process of delivery, some patients return before the 37th week of pregnancy with recurrence of preterm labor signs. objectives this study was designed to evaluate the efficacy of progesterone in the prolonging of gestation and reduction of neonatal complications. material and methods in a clinical trial in 2010, 110 singleton pregnant women admitt...

OBJECTIVES This study was done to compare isoxpurine hydrochloride and nifedipine as tocolytic drugs for preterm labor. METHODS A prospective cohort study of 832 antenatal women with preterm labor was conducted in the Department of Obstetrics & Gynecology. Out of 400 women found eligible for tocolysis, 200 were given isoxpurine hydrochloride while the other 200 were given nifedipine randomly....

PURPOSE To evaluate the proportional changes of CD4+CD25+Foxp3+ regulatory T cells (Tregs) in maternal peripheral blood during pregnancy and labor at term and preterm. METHODS Peripheral blood was collected from 20 non-pregnant controls and 139 pregnant women (60 at different gestational ages, 48 at term with or without labor, and 31 in threatened or actual preterm labor). CD4+CD25+Foxp3+ Tre...

Background: Preterm birth is the major cause of neonatal mortality and morbidity. In developing countries, it’s a major health hazard. But there are very few evidence based interventions to prevent it. This study focus on prevention of preterm birth. Methods: A randomized controlled trial was undertaken in BP Koirala Institute of Health Sciences, where 60 patients were randomized into group 1 (...